Varaico: Literature-Extracted Genetic Variants

Gene:DCK
Variant:p.A119G
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DCK

NM_000788.3:p.A119G

Associated Papers

dCK Expression and Gene Polymorphism With Gemcitabine Chemosensitivity in Patients With Pancreatic Ductal Adenocarcinoma: A Strobe-Compliant Observational Study.

Xiong J et al.

Medicine, 2016

Acquisition of chemoresistance to gemcitabine is induced by a loss-of-function missense mutation of DCK.

Nakano T et al.

Biochemical and Biophysical Research Communications, 2015

Impact of single nucleotide polymorphisms of cytarabine metabolic genes on drug toxicity in childhood acute lymphoblastic leukemia.

Gabor KM et al.

Pediatric Blood & Cancer, 2015

Pharmacogenomics of gemcitabine metabolism: functional analysis of genetic variants in cytidine deaminase and deoxycytidine kinase.

Baker JA et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2013

The influence of gemcitabine pathway polymorphisms on treatment outcome in patients with malignant mesothelioma.

Erčulj N et al.

Pharmacogenetics and Genomics, 2012

Pharmacogenetics and pharmacoepigenetics of gemcitabine.

Candelaria M et al.

Medical Oncology (northwood, London, England), 2010

Genetic factors influencing cytarabine therapy.

Lamba JK

Pharmacogenomics, 2009

Gemcitabine pharmacogenomics: deoxycytidine kinase and cytidylate kinase gene resequencing and functional genomics.

Kocabas NA et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2008

Pharmacogenetics of deoxycytidine kinase: identification and characterization of novel genetic variants.

Lamba JK et al.

The Journal of Pharmacology and Experimental Therapeutics, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."