Varaico: Literature-Extracted Genetic Variants

Gene:DCK
Variant:p.P122S
Back to variants list

DCK

NM_000788.3:p.P122S

Associated Papers

Integrated multi-omics analysis reveals the involvement of the gut-brain axis in children with autism.

Zhong H et al.

Frontiers in Microbiology, 2026

41716284 (PubMed )
Supplement: Supplementary_file_2.xlsx › Table_S1

The pharmacogenomic landscape in the Chinese: An analytics of pharmacogenetic variants in 206,640 individuals.

Wang LY et al.

Innovation (cambridge (mass.)), 2025

39991480 (PubMed )
Supplement: mmc5.xlsx › Sheet1

ACE Phenotyping in Human Blood and Tissues: Revelation of ACE Outliers and Sex Differences in ACE Sialylation.

Enyedi EE et al.

Biomedicines, 2024

38790902 (PubMed )
Supplement: biomedicines-12-00940-s001.zip › biomedicines-2930173-supplementary.pdf

Immunogenomic analysis of human brain metastases reveals diverse immune landscapes across genetically distinct tumors.

Álvarez-Prado ÁF et al.

Cell Reports. Medicine, 2023

36652909 (PubMed )
Supplement: mmc8.xlsx › BrM167

Validating Amino Acid Variants in Proteogenomics Using Sequence Coverage by Multiple Reads.

Levitsky LI et al.

Journal of Proteome Research, 2022

35536917 (PubMed )
Supplement: pr2c00033_si_002.pdf

Association between DCK 35708 T>C variation and clinical outcomes of acute myeloid leukemia in South Chinese patients.

Zhang DY et al.

Pharmacogenomics, 2016

Exome-based proteogenomics of HEK-293 human cell line: Coding genomic variants identified at the level of shotgun proteome.

Lobas AA et al.

Proteomics, 2016

The clinical implication of single nucleotide polymorphisms in deoxycytidine kinase in chronic hepatitis B patients treated with lamivudine.

Lee HW et al.

Journal of Medical Virology, 2016

dCK Expression and Gene Polymorphism With Gemcitabine Chemosensitivity in Patients With Pancreatic Ductal Adenocarcinoma: A Strobe-Compliant Observational Study.

Xiong J et al.

Medicine, 2016

Acquisition of chemoresistance to gemcitabine is induced by a loss-of-function missense mutation of DCK.

Nakano T et al.

Biochemical and Biophysical Research Communications, 2015

Impact of single nucleotide polymorphisms of cytarabine metabolic genes on drug toxicity in childhood acute lymphoblastic leukemia.

Gabor KM et al.

Pediatric Blood & Cancer, 2015

Pharmacogenomics of gemcitabine metabolism: functional analysis of genetic variants in cytidine deaminase and deoxycytidine kinase.

Baker JA et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2013

The influence of gemcitabine pathway polymorphisms on treatment outcome in patients with malignant mesothelioma.

Erčulj N et al.

Pharmacogenetics and Genomics, 2012

Pharmacogenetics and pharmacoepigenetics of gemcitabine.

Candelaria M et al.

Medical Oncology (northwood, London, England), 2010

Population pharmacokinetics of gemcitabine and its metabolite in Japanese cancer patients: impact of genetic polymorphisms.

Sugiyama E et al.

Clinical Pharmacokinetics, 2010

Genetic factors influencing cytarabine therapy.

Lamba JK

Pharmacogenomics, 2009

Homozygous CDA*3 is a major cause of life-threatening toxicities in gemcitabine-treated Japanese cancer patients.

Ueno H et al.

British Journal of Cancer, 2009

Gemcitabine pharmacogenomics: deoxycytidine kinase and cytidylate kinase gene resequencing and functional genomics.

Kocabas NA et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2008

Twenty novel genetic variations and haplotype structures of the DCK gene encoding human deoxycytidine kinase (dCK).

Kim SR et al.

Drug Metabolism and Pharmacokinetics, 2008

Pharmacogenetics of deoxycytidine kinase: identification and characterization of novel genetic variants.

Lamba JK et al.

The Journal of Pharmacology and Experimental Therapeutics, 2007

Novel deoxycytidine kinase gene polymorphisms: a population screening study in Caucasian healthy volunteers.

Joerger M et al.

European Journal of Clinical Pharmacology, 2006

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."