Varaico: Literature-Extracted Genetic Variants

Gene:DCK
Variant:p.D133A
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DCK

NM_000788.3:p.D133A

Associated Papers

Potent Sensitisation of Cancer Cells to Anticancer Drugs by a Quadruple Mutant of the Human Deoxycytidine Kinase.

Coulibaly ST et al.

Plos One, 2015

Redesigning human 2'-deoxycytidine kinase enantioselectivity for L-nucleoside analogues as reporters in positron emission tomography.

Muthu P et al.

Acs Chemical Biology, 2014

Deoxycytidine kinase augments ATM-Mediated DNA repair and contributes to radiation resistance.

Bunimovich YL et al.

Plos One, 2014

Retrovolution: HIV-driven evolution of cellular genes and improvement of anticancer drug activation.

Rossolillo P et al.

Plos Genetics, 2012

Post-translational phosphorylation of serine 74 of human deoxycytidine kinase favors the enzyme adopting the open conformation making it competent for nucleoside binding and release.

Hazra S et al.

Biochemistry, 2011

Structural and kinetic characterization of human deoxycytidine kinase variants able to phosphorylate 5-substituted deoxycytidine and thymidine analogues .

Hazra S et al.

Biochemistry, 2010

Extending thymidine kinase activity to the catalytic repertoire of human deoxycytidine kinase.

Hazra S et al.

Biochemistry, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."