Associated Papers
Human DCP1 is crucial for mRNA decapping and possesses paralog-specific gene regulating functions.
Chen TW et al.
Elife, 2024
Human Pumilio proteins directly bind the CCR4-NOT deadenylase complex to regulate the transcriptome.
Enwerem III et al.
Rna (new York, N.y.), 2021
HELZ directly interacts with CCR4-NOT and causes decay of bound mRNAs.
Hanet A et al.
Life Science Alliance, 2019
A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4-NOT complex.
Keskeny C et al.
Genes & Development, 2019
A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin.
Sgromo A et al.
Nature Communications, 2017
Structural basis for the Nanos-mediated recruitment of the CCR4-NOT complex and translational repression.
Bhandari D et al.
Genes & Development, 2014
The SMG5-SMG7 heterodimer directly recruits the CCR4-NOT deadenylase complex to mRNAs containing nonsense codons via interaction with POP2.
Loh B et al.
Genes & Development, 2013
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