Associated Papers
A scalable approach to resolving variants of uncertain significance.
Tejura M et al.
Biorxiv : the Preprint Server for Biology, 2026
Doublecortin restricts neuronal branching by regulating tubulin polyglutamylation.
Sébastien M et al.
Nature Communications, 2025
Pervasive mislocalization of pathogenic coding variants underlying human disorders.
Lacoste J et al.
Cell, 2024
Pervasive mislocalization of pathogenic coding variants underlying human disorders.
Lacoste J et al.
Biorxiv : the Preprint Server for Biology, 2023
ConVarT: a search engine for matching human genetic variants with variants from non-human species.
Pir MS et al.
Nucleic Acids Research, 2022
Pseudo-repeats in doublecortin make distinct mechanistic contributions to microtubule regulation.
Manka SW et al.
Embo Reports, 2020
Different Doublecortin (DCX) Patient Alleles Show Distinct Phenotypes in Cultured Neurons: EVIDENCE FOR DIVERGENT LOSS-OF-FUNCTION AND "OFF-PATHWAY" CELLULAR MECHANISMS.
Yap CC et al.
The Journal of Biological Chemistry, 2016
Doublecortin (Dcx) family proteins regulate filamentous actin structure in developing neurons.
Fu X et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2013
Molecular basis for specific regulation of neuronal kinesin-3 motors by doublecortin family proteins.
Liu JS et al.
Molecular Cell, 2012
Phosphorylation of doublecortin by protein kinase A orchestrates microtubule and actin dynamics to promote neuronal progenitor cell migration.
Toriyama M et al.
The Journal of Biological Chemistry, 2012
Missense mutations resulting in type 1 lissencephaly.
Reiner O et al.
Cellular and Molecular Life Sciences : Cmls, 2005
The DCX-domain tandems of doublecortin and doublecortin-like kinase.
Kim MH et al.
Nature Structural Biology, 2003
Mutation analysis of the DCX gene and genotype/phenotype correlation in subcortical band heterotopia.
Matsumoto N et al.
European Journal of Human Genetics : Ejhg, 2001
Doublecortin mutations cluster in evolutionarily conserved functional domains.
Sapir T et al.
Human Molecular Genetics, 2000
Characterization of mutations in the gene doublecortin in patients with double cortex syndrome.
Gleeson JG et al.
Annals of Neurology, 1999