Varaico: Literature-Extracted Genetic Variants

Gene:DDR2
Variant:p.L63V
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DDR2

NM_006182.4:p.L63V

Associated Papers

Frequency enrichment of coding variants in a French-Canadian founder population and its implication for inflammatory bowel diseases.

Bhérer C et al.

Medrxiv : the Preprint Server for Health Sciences, 2025

40791678 (PubMed )
Supplement: media-2.xlsx › Table_S12_ClinVar_PLP_variants

Potentially functional variants of PARK7 and DDR2 in ferroptosis-related genes predict survival of non-small cell lung cancer patients.

Wang H et al.

International Journal of Cancer, 2025

Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder.

Jia X et al.

Molecular Psychiatry, 2021

33483695 (PubMed )
Supplement: 41380_2020_1006_MOESM2_ESM.xlsx › S2

Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Hescheler DA et al.

Frontiers in Endocrinology, 2021

34630336 (PubMed )
Supplement: Table_1.xlsx › Tab2

Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

Li J et al.

Journal of Translational Medicine, 2020

32738923 (PubMed )
Supplement: 12967_2020_2449_MOESM2_ESM.xlsx › Supplementary_Table_S1

Family History of Colorectal or Esophageal Cancer in Barrett's Esophagus and Potentially Explanatory Genetic Variants.

Rubenstein JH et al.

Clinical and Translational Gastroenterology, 2020

Disruption of the PTHLH regulatory landscape results in features consistent with hyperparathyroid disease.

Deshwar AR et al.

American Journal of Medical Genetics. Part A, 2019

Integrative omics analyses broaden treatment targets in human cancer.

Sengupta S et al.

Genome Medicine, 2018

30053901 (PubMed )
Supplement: 13073_2018_564_MOESM2_ESM.xlsx › 3

Lung Cancers: Molecular Characterization, Clonal Heterogeneity and Evolution, and Cancer Stem Cells.

Testa U et al.

Cancers, 2018

Prevalence of Mutations in Discoidin Domain-Containing Receptor Tyrosine Kinase 2 (DDR2) in Squamous Cell Lung Cancers in Korean Patients.

Lee MS et al.

Cancer Research and Treatment, 2017

Functional analysis of Discoidin domain receptor 2 mutation and expression in squamous cell lung cancer.

Kobayashi-Watanabe N et al.

Lung Cancer (amsterdam, Netherlands), 2017

Functional Analyses of Mutations in Receptor Tyrosine Kinase Genes in Non-Small Cell Lung Cancer: Double-Edged Sword of DDR2.

Terashima M et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2016

NSCLC Driven by DDR2 Mutation Is Sensitive to Dasatinib and JQ1 Combination Therapy.

Xu C et al.

Molecular Cancer Therapeutics, 2015

Racial diversity of actionable mutations in non-small cell lung cancer.

Bollig-Fischer A et al.

Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer, 2015

Tongue carcinoma infrequently harbor common actionable genetic alterations.

Tan DS et al.

Bmc Cancer, 2014

Discoidin domain receptor 2 signaling networks and therapy in lung cancer.

Payne LS et al.

Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer, 2014

Multiplex genomic profiling of non-small cell lung cancers from the LETS phase III trial of first-line S-1/carboplatin versus paclitaxel/carboplatin: results of a West Japan Oncology Group study.

Okamoto I et al.

Oncotarget, 2014

24810493 (PubMed )
Supplement: oncotarget-05-2293-s001.pdf

Collagen recognition and transmembrane signalling by discoidin domain receptors.

Carafoli F et al.

Biochimica Et Biophysica Acta, 2013

Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer mutants.

Iwai LK et al.

The Biochemical Journal, 2013

Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer.

Hammerman PS et al.

Cancer Discovery, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."