Varaico: Literature-Extracted Genetic Variants

Gene:DDR2
Variant:p.L239R
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DDR2

NM_006182.4:p.L239R

Associated Papers

Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Hescheler DA et al.

Frontiers in Endocrinology, 2021

34630336 (PubMed )
Supplement: Table_1.xlsx › Tab2

Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

Li J et al.

Journal of Translational Medicine, 2020

32738923 (PubMed )
Supplement: 12967_2020_2449_MOESM2_ESM.xlsx › Supplementary_Table_S1

Integrative omics analyses broaden treatment targets in human cancer.

Sengupta S et al.

Genome Medicine, 2018

30053901 (PubMed )
Supplement: 13073_2018_564_MOESM2_ESM.xlsx › 3

Precision medicine for urothelial bladder cancer: update on tumour genomics and immunotherapy.

Felsenstein KM et al.

Nature Reviews. Urology, 2018

Prevalence of Mutations in Discoidin Domain-Containing Receptor Tyrosine Kinase 2 (DDR2) in Squamous Cell Lung Cancers in Korean Patients.

Lee MS et al.

Cancer Research and Treatment, 2017

The evolving genomic landscape of urothelial carcinoma.

Glaser AP et al.

Nature Reviews. Urology, 2017

Characterization of DDR2 Inhibitors for the Treatment of DDR2 Mutated Nonsmall Cell Lung Cancer.

Terai H et al.

Acs Chemical Biology, 2015

NSCLC Driven by DDR2 Mutation Is Sensitive to Dasatinib and JQ1 Combination Therapy.

Xu C et al.

Molecular Cancer Therapeutics, 2015

Adaptive responses to dasatinib-treated lung squamous cell cancer cells harboring DDR2 mutations.

Bai Y et al.

Cancer Research, 2014

Sensitive methods for detection of the S768R substitution in exon 18 of the DDR2 gene in patients with central nervous system metastases of non-small cell lung cancer.

Nicoś M et al.

Medical Oncology (northwood, London, England), 2014

Tongue carcinoma infrequently harbor common actionable genetic alterations.

Tan DS et al.

Bmc Cancer, 2014

Multiplex genomic profiling of non-small cell lung cancers from the LETS phase III trial of first-line S-1/carboplatin versus paclitaxel/carboplatin: results of a West Japan Oncology Group study.

Okamoto I et al.

Oncotarget, 2014

24810493 (PubMed )
Supplement: oncotarget-05-2293-s001.pdf

Acquired resistance to dasatinib in lung cancer cell lines conferred by DDR2 gatekeeper mutation and NF1 loss.

Beauchamp EM et al.

Molecular Cancer Therapeutics, 2014

Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer.

Hammerman PS et al.

Cancer Discovery, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."