Varaico: Literature-Extracted Genetic Variants

Gene:DDR2
Variant:p.Y740F
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DDR2

NM_006182.4:p.Y740F

Associated Papers

Warburg-Cinotti disease variant p.Tyr740Cys enhances catalytic activity of DDR2 kinase.

Hao Z et al.

Plos One, 2025

DDR2 upregulation confers ferroptosis susceptibility of recurrent breast tumors through the Hippo pathway.

Lin CC et al.

Oncogene, 2021

Recurrent, Activating Variants in the Receptor Tyrosine Kinase DDR2 Cause Warburg-Cinotti Syndrome.

Xu L et al.

American Journal of Human Genetics, 2018

Ubiquitin ligase Cbl-b acts as a negative regulator in discoidin domain receptor 2 signaling via modulation of its stability.

Yu J et al.

Febs Letters, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."