Associated Papers
The clinical and molecular landscape of breast cancer in women of African and South Asian ancestry.
Thorn GJ et al.
Nature Communications, 2025
Targeting DDX11 promotes PARP inhibitor sensitivity in hepatocellular carcinoma by attenuating BRCA2-RAD51 mediated homologous recombination.
Cao K et al.
Oncogene, 2024
Targeting the non-coding genome and temozolomide signature enables CRISPR-mediated glioma oncolysis.
Tan IL et al.
Cell Reports, 2023
[Warsaw breakage syndrome: an etiology for congenital microcephaly and sensorineural deafness].
Arroyo-Carrera I et al.
Revista De Neurologia, 2023
Genomic integrity and mitochondrial metabolism defects in Warsaw syndrome cells: a comparison with Fanconi anemia.
Bottega R et al.
Journal of Cellular Physiology, 2021
DDX11 loss causes replication stress and pharmacologically exploitable DNA repair defects.
Jegadesan NK et al.
Proceedings of the National Academy of Sciences of the United States of America, 2021
Role of the DDX11 DNA Helicase in Warsaw Breakage Syndrome Etiology.
Santos D et al.
International Journal of Molecular Sciences, 2021
High-depth African genomes inform human migration and health.
Choudhury A et al.
Nature, 2020
Warsaw Breakage Syndrome associated DDX11 helicase resolves G-quadruplex structures to support sister chromatid cohesion.
van Schie JJM et al.
Nature Communications, 2020
The iron-sulfur helicase DDX11 promotes the generation of single-stranded DNA for CHK1 activation.
Simon AK et al.
Life Science Alliance, 2020
Workflow for the Implementation of Precision Genomics in Healthcare.
Mehandziska S et al.
Frontiers in Genetics, 2020
Systematic analysis of the intersection of disease mutations with protein modifications.
Simpson CM et al.
Bmc Medical Genomics, 2019
Spotlight on Warsaw Breakage Syndrome.
Pisani FM
The Application of Clinical Genetics, 2019
Molecular and Cellular Functions of the Warsaw Breakage Syndrome DNA Helicase DDX11.
Pisani FM et al.
Genes, 2018
Warsaw breakage syndrome: Further clinical and genetic delineation.
Alkhunaizi E et al.
American Journal of Medical Genetics. Part A, 2018
Hsp90 Is Essential for Chl1-Mediated Chromosome Segregation and Sister Chromatid Cohesion.
Khurana N et al.
Msphere, 2018
Iron-sulfur cluster biosynthesis and trafficking - impact on human disease conditions.
Wachnowsky C et al.
Metallomics : Integrated Biometal Science, 2018
Mutational analysis of FANCJ helicase.
Guo M et al.
Methods (san Diego, Calif.), 2016
Patterns and functional implications of rare germline variants across 12 cancer types.
Lu C et al.
Nature Communications, 2015
The Warsaw breakage syndrome-related protein DDX11 is required for ribosomal RNA synthesis and embryonic development.
Sun X et al.
Human Molecular Genetics, 2015
GESPA: classifying nsSNPs to predict disease association.
Khurana JK et al.
Bmc Bioinformatics, 2015
Warsaw Breakage Syndrome--A further report, emphasising cutaneous findings.
Bailey C et al.
European Journal of Medical Genetics, 2015
The Q Motif Is Involved in DNA Binding but Not ATP Binding in ChlR1 Helicase.
Ding H et al.
Plos One, 2015
Molecular functions and cellular roles of the ChlR1 (DDX11) helicase defective in the rare cohesinopathy Warsaw breakage syndrome.
Bharti SK et al.
Cellular and Molecular Life Sciences : Cmls, 2014
Identification and biochemical characterization of a novel mutation in DDX11 causing Warsaw breakage syndrome.
Capo-Chichi JM et al.
Human Mutation, 2013
Disease-causing missense mutations in human DNA helicase disorders.
Suhasini AN et al.
Mutation Research, 0