Associated Papers
Specific catalytically impaired DDX3X mutants form sexually dimorphic hollow condensates.
Owens MC et al.
Nature Communications, 2024
The Role of the RNA Helicase DDX3X in Medulloblastoma Progression.
Swarup A et al.
Biomolecules, 2024
Author Correction: Cancer-associated DDX3X mutations drive stress granule assembly and impair global translation.
Valentin-Vega YA et al.
Scientific Reports, 2024
NMR characterization of RNA binding property of the DEAD-box RNA helicase DDX3X and its implications for helicase activity.
Toyama Y et al.
Nature Communications, 2024
Saturation genome editing of DDX3X clarifies pathogenicity of germline and somatic variation.
Radford EJ et al.
Nature Communications, 2023
38057330 (PubMed )
Supplement: 41467_2023_43041_MOESM4_ESM.zip › Supplementary_Data › Supplementary_Data_S26_cBioportal_DDX3X_vars_190_nonoverlapping_samples.xlsx › Supplementary_Data_S21_cBioport
Mutant forms of DDX3X with diminished catalysis form hollow condensates that exhibit sex-specific regulation.
Owens MC et al.
Biorxiv : the Preprint Server for Biology, 2023
The human DEAD-box helicase DDX3X as a regulator of mRNA translation.
Ryan CS et al.
Frontiers in Cell and Developmental Biology, 2022
Targeting DDX3X Triggers Antitumor Immunity via a dsRNA-Mediated Tumor-Intrinsic Type I Interferon Response.
Choi H et al.
Cancer Research, 2021
Mutant Proteomics of Lung Adenocarcinomas Harboring Different EGFR Mutations.
Nishimura T et al.
Frontiers in Oncology, 2020
32983988 (PubMed )
Supplement: Data_Sheet_2.xlsx › AZ028
CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation.
Cheng W et al.
Neuron, 2019
Cancer-associated DDX3X mutations drive stress granule assembly and impair global translation.
Valentin-Vega YA et al.
Scientific Reports, 2016
Cancer-associated mutants of RNA helicase DDX3X are defective in RNA-stimulated ATP hydrolysis.
Epling LB et al.
Journal of Molecular Biology, 2015
Novel mutations target distinct subgroups of medulloblastoma.
Robinson G et al.
Nature, 2012
22722829 (PubMed )
Supplement: NIHMS374717-supplement-info.pdf
Medulloblastoma-associated mutations in the DEAD-box RNA helicase DDX3X/DED1 cause specific defects in translation.
Brown NP et al.
The Journal of Biological Chemistry, 0
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