Varaico: Literature-Extracted Genetic Variants

Gene:DDX5
Variant:p.K144N
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DDX5

NM_004396.5:p.K144N

Associated Papers

Targeting DDX5 using FL118 suppresses mTOR signaling and tumorigenicity in JAK2V617F-driven myeloproliferative neoplasms.

Takeda K et al.

International Immunopharmacology, 2026

RNA helicase DDX5 enables STAT1 mRNA translation and interferon signalling in hepatitis B virus replicating hepatocytes.

Sun J et al.

Gut, 2022

Characterization of the mammalian DEAD-box protein DDX5 reveals functional conservation with S. cerevisiae ortholog Dbp2 in transcriptional control and glucose metabolism.

Xing Z et al.

Rna (new York, N.y.), 2017

RNA helicase Ddx5 and the noncoding RNA SRA act as coactivators in the Notch signaling pathway.

Jung C et al.

Biochimica Et Biophysica Acta, 2013

The variable N-terminal region of DDX5 contains structural elements and auto-inhibits its interaction with NS5B of hepatitis C virus.

Dutta S et al.

The Biochemical Journal, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."