Associated Papers
DEPTOR at the Nexus of Cancer, Metabolism, and Immunity.
Caron A et al.
Physiological Reviews, 2018
mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR.
Gao D et al.
Molecular Cell, 2011
mTOR generates an auto-amplification loop by triggering the βTrCP- and CK1α-dependent degradation of DEPTOR.
Duan S et al.
Molecular Cell, 2011
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