Associated Papers
Insights into DEPTOR regulation from in silico analysis of DEPTOR complexes.
Teh AH et al.
Journal of Structural Biology, 2020
mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR.
Gao D et al.
Molecular Cell, 2011
mTOR generates an auto-amplification loop by triggering the βTrCP- and CK1α-dependent degradation of DEPTOR.
Duan S et al.
Molecular Cell, 2011
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