Varaico: Literature-Extracted Genetic Variants

Gene:DHFR
Variant:p.L28F
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DHFR

NM_000791.4:p.L28F

Associated Papers

Computational protein design repurposed to explore enzyme vitality and help predict antibiotic resistance.

Michael E et al.

Frontiers in Molecular Biosciences, 2022

Altered expression of a quality control protease in E. coli reshapes the in vivo mutational landscape of a model enzyme.

Thompson S et al.

Elife, 2020

32701056 (PubMed )
Supplement: elife-53476-fig1-data2.xlsx › Sheet1

Substrate and inhibitor specificity of Mycobacterium avium dihydrofolate reductase.

Böck RA et al.

The Febs Journal, 2007

Molecular basis for nonadditive mutational effects in Escherichia coli dihydrofolate reductase.

Wagner CR et al.

Biochemistry, 1995

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."