Varaico: Literature-Extracted Genetic Variants

Gene:DHFR
Variant:p.L5Q
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DHFR

NM_000791.4:p.L5Q

Associated Papers

Deep mutational scanning of Pneumocystis jirovecii dihydrofolate reductase reveals allosteric mechanism of resistance to an antifolate.

Rouleau FD et al.

Plos Genetics, 2024

38683847 (PubMed )
Supplement: pgen.1011252.s019.xlsx › Curration_file

Trimethoprim resistance of dihydrofolate reductase variants from clinical isolates of Pneumocystis jirovecii.

Queener SF et al.

Antimicrobial Agents and Chemotherapy, 2013

Mutations of Pneumocystis jirovecii dihydrofolate reductase associated with failure of prophylaxis.

Nahimana A et al.

Antimicrobial Agents and Chemotherapy, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."