Varaico: Literature-Extracted Genetic Variants

Gene:DHPS
Variant:p.D243A
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DHPS

NM_001930.4:p.D243A

Associated Papers

ERK1/2 interaction with DHPS regulates eIF5A deoxyhypusination independently of ERK kinase activity.

Becker AE et al.

Cell Reports, 2024

A genome-wide CRISPR functional survey of the human phagocytosis molecular machinery.

Essletzbichler P et al.

Life Science Alliance, 2023

Cryo-EM structure of human eIF5A-DHS complex reveals the molecular basis of hypusination-associated neurodegenerative disorders.

Wątor E et al.

Nature Communications, 2023

Structure-function studies of human deoxyhypusine synthase: identification of amino acid residues critical for the binding of spermidine and NAD.

Lee CH et al.

The Biochemical Journal, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."