Associated Papers
Deciphering the Impact of Mutations on PfDHPS Active Site and Sulfadoxine Binding: Structural Insights from Molecular Dynamics Simulations.
Guémas E et al.
Molecules (basel, Switzerland), 2025
Clonal Transmission of Emerging Novel Plasmodium falciparum Kelch13 Mutations and Increasing Complexity of Infection in Libreville, Gabon, 2021-2023.
Ndong Ngomo JM et al.
Medrxiv : the Preprint Server for Health Sciences, 2025
Artemisinin Partial Resistance Mutations in Zanzibar and Tanzania Suggest Regional Spread and African Origins, 2023.
Connelly SV et al.
Medrxiv : the Preprint Server for Health Sciences, 2025
National genomic profiling of Plasmodium falciparum antimalarial resistance in Zambian children participating in the 2018 Malaria Indicator Survey.
Fola AA et al.
Medrxiv : the Preprint Server for Health Sciences, 2024
Expansion of artemisinin partial resistance mutations and lack of histidine rich protein-2 and -3 deletions in Plasmodium falciparum infections from Rukara, Rwanda.
Schreidah C et al.
Malaria Journal, 2024
Plasmodium falciparum drug resistance-associated mutations in isolates from children living in endemic areas of Burkina Faso.
Tarama CW et al.
Malaria Journal, 2023
Drug resistance of Plasmodium falciparum and Plasmodium vivax isolates in Indonesia.
Rahmasari FV et al.
Malaria Journal, 2022
Genomic analysis of single nucleotide polymorphisms in malaria parasite drug targets.
Gill J et al.
Parasites & Vectors, 2022
Screening for antifolate and artemisinin resistance in Plasmodium falciparum dried-blood spots from three hospitals of Eritrea.
Mukhongo HN et al.
F1000research, 2021
Changes in the frequencies of Plasmodium falciparum dhps and dhfr drug-resistant mutations in children from Western Kenya from 2005 to 2018: the rise of Pfdhps S436H.
Pacheco MA et al.
Malaria Journal, 2020
The structure of Plasmodium falciparum hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase reveals the basis of sulfa resistance.
Chitnumsub P et al.
The Febs Journal, 2020
Assessment of Plasmodium falciparum drug resistance molecular markers from the Blue Nile State, Southeast Sudan.
Mohamed AO et al.
Malaria Journal, 2020
Structure of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase-dihydropteroate synthase from Plasmodium vivax sheds light on drug resistance.
Yogavel M et al.
The Journal of Biological Chemistry, 2018
Nanopore sequencing of drug-resistance-associated genes in malaria parasites, Plasmodium falciparum.
Runtuwene LR et al.
Scientific Reports, 2018
Prevalence of the Pfdhfr and Pfdhps mutations among asymptomatic pregnant women in Southeast Nigeria.
Esu E et al.
Parasitology Research, 2018
Molecular identification of sulfadoxine-pyrimethamine resistance in malaria infected women who received intermittent preventive treatment in the Democratic Republic of Congo.
Ruh E et al.
Malaria Journal, 2018
Characterization of Plasmodium falciparum genes associated with drug resistance in Hodh Elgharbi, a malaria hotspot near Malian-Mauritanian border.
Ould Ahmedou Salem MS et al.
Malaria Journal, 2017
Increasing prevalence of a novel triple-mutant dihydropteroate synthase genotype in Plasmodium falciparum in western Kenya.
Lucchi NW et al.
Antimicrobial Agents and Chemotherapy, 2015
Independent origin of plasmodium falciparum antifolate super-resistance, Uganda, Tanzania, and Ethiopia.
Alifrangis M et al.
Emerging Infectious Diseases, 2014
Malaria treatment failure with novel mutation in the Plasmodium falciparum dihydrofolate reductase (pfdhfr) gene in Kolkata, West Bengal, India.
Das S et al.
International Journal of Antimicrobial Agents, 2013
Whole genome re-sequencing identifies a mutation in an ABC transporter (mdr2) in a Plasmodium chabaudi clone with altered susceptibility to antifolate drugs.
Martinelli A et al.
International Journal for Parasitology, 2011
Anti-folate drug resistance in Africa: meta-analysis of reported dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutant genotype frequencies in African Plasmodium falciparum parasite populations.
Sridaran S et al.
Malaria Journal, 2010
Origin and evolution of sulfadoxine resistant Plasmodium falciparum.
Vinayak S et al.
Plos Pathogens, 2010
The implication of dihydrofolate reductase and dihydropteroate synthetase gene mutations in modification of Plasmodium falciparum characteristics.
A-Elbasit IE et al.
Malaria Journal, 2007
Plasmodium falciparum isolates in India exhibit a progressive increase in mutations associated with sulfadoxine-pyrimethamine resistance.
Ahmed A et al.
Antimicrobial Agents and Chemotherapy, 2004
Prevalence of point mutations in the dihydrofolate reductase and dihydropteroate synthetase genes of Plasmodium falciparum isolates from India and Thailand: a molecular epidemiologic study.
Biswas S et al.
Tropical Medicine & International Health : Tm & Ih, 2000
Allelic exchange at the endogenous genomic locus in Plasmodium falciparum proves the role of dihydropteroate synthase in sulfadoxine-resistant malaria.
Triglia T et al.
The Embo Journal, 1998