Associated Papers
Clinical experience of using integrated whole genome and transcriptome sequencing as a framework for pediatric and adolescent acute myeloid leukemia diagnosis and risk assessment.
Voss RK et al.
Leukemia, 2025
A new genomic framework to categorize pediatric acute myeloid leukemia.
Umeda M et al.
Nature Genetics, 2024
A helicase-independent role of DHX15 promotes MYC stability and acute leukemia cell survival.
Li Q et al.
Iscience, 2024
Identification of DHX40 as a candidate susceptibility gene for colorectal and hematological neoplasia.
Olkinuora A et al.
Leukemia, 2023
Splicing quality control mediated by DHX15 and its G-patch activator SUGP1.
Feng Q et al.
Cell Reports, 2023
Transcriptome-based molecular subtypes and differentiation hierarchies improve the classification framework of acute myeloid leukemia.
Cheng WY et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022
DHX15 is involved in SUGP1-mediated RNA missplicing by mutant SF3B1 in cancer.
Zhang J et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022
Genomic landscape of patients with FLT3-mutated acute myeloid leukemia (AML) treated within the CALGB 10603/RATIFY trial.
Jahn N et al.
Leukemia, 2022
The RNA helicase DHX15 is a critical regulator of natural killer-cell homeostasis and functions.
Wang G et al.
Cellular & Molecular Immunology, 2022
Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia.
Umeda M et al.
Blood Cancer Discovery, 2022
Distinct genomic landscape of Chinese pediatric acute myeloid leukemia impacts clinical risk classification.
Liu T et al.
Nature Communications, 2022
Genomes for Kids: The Scope of Pathogenic Mutations in Pediatric Cancer Revealed by Comprehensive DNA and RNA Sequencing.
Newman S et al.
Cancer Discovery, 2021
Integrative Genomic Analysis of Pediatric Myeloid-Related Acute Leukemias Identifies Novel Subtypes and Prognostic Indicators.
Fornerod M et al.
Blood Cancer Discovery, 2021
Dhx15 regulates zebrafish definitive hematopoiesis through the unfolded protein response pathway.
Cai Y et al.
Cancer Science, 2021
The clinical mutatome of core binding factor leukemia.
Opatz S et al.
Leukemia, 2020
Splicing factor DHX15 affects tp53 and mdm2 expression via alternate splicing and promoter usage.
McElderry J et al.
Human Molecular Genetics, 2019
Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours.
Ma X et al.
Nature, 2018
The genomic landscape of pediatric myelodysplastic syndromes.
Schwartz JR et al.
Nature Communications, 2017
RNA helicase DHX15 acts as a tumour suppressor in glioma.
Ito S et al.
British Journal of Cancer, 2017
The genomic landscape of core-binding factor acute myeloid leukemias.
Faber ZJ et al.
Nature Genetics, 2016