Varaico: Literature-Extracted Genetic Variants

Gene:DHX34
Variant:p.D279A
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DHX34

NM_014681.6:p.D279A

Associated Papers

A dual role for the RNA helicase DHX34 in NMD and pre-mRNA splicing and its function in hematopoietic differentiation.

Hug N et al.

Rna (new York, N.y.), 2022

Regulation of RUVBL1-RUVBL2 AAA-ATPases by the nonsense-mediated mRNA decay factor DHX34, as evidenced by Cryo-EM.

López-Perrote A et al.

Elife, 2020

33205750 (PubMed )
Supplement: elife-63042-fig5-data1.zip › Figure_5__source_data.xlsx › Figure5_S1_source_9

The RNA helicase DHX34 functions as a scaffold for SMG1-mediated UPF1 phosphorylation.

Melero R et al.

Nature Communications, 2016

The RNA helicase DHX34 activates NMD by promoting a transition from the surveillance to the decay-inducing complex.

Hug N et al.

Cell Reports, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."