Varaico: Literature-Extracted Genetic Variants

Gene:DHX58
Variant:p.K651E
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DHX58

NM_024119.3:p.K651E

Associated Papers

Effect of variants in LGP2 on MDA5-mediated activation of interferon response and suppression of hepatitis D virus replication.

Gillich N et al.

Journal of Hepatology, 2023

Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.

Uchikawa E et al.

Molecular Cell, 2016

27203181 (PubMed )
Supplement: mmc1.pdf

ATP hydrolysis enhances RNA recognition and antiviral signal transduction by the innate immune sensor, laboratory of genetics and physiology 2 (LGP2).

Bruns AM et al.

The Journal of Biological Chemistry, 2013

Identification of loss of function mutations in human genes encoding RIG-I and MDA5: implications for resistance to type I diabetes.

Shigemoto T et al.

The Journal of Biological Chemistry, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."