Associated Papers
Integrating evidence from protein domains to identify cancer driver mutations.
Ostroverkhova D et al.
Protein Science : a Publication of the Protein Society, 2026
Mutation-tissue specificity in DICER1 syndrome: insights from familial pleuropulmonary blastoma and a pan-tumour hotspot analysis.
Yang G et al.
Pathology, 2026
DICER1 Mutational Spectrum in Intracranial CNS-Neoplasias-A Review and a Report from the CNS-InterREST GPOH Study Center.
Manea S et al.
Cancers, 2025
Stratified Medicine Pediatrics: Cell-Free DNA and Serial Tumor Sequencing Identifies Subtype-Specific Cancer Evolution and Epigenetic States.
George SL et al.
Cancer Discovery, 2025
Prognostic Significance of Germline DICER1 Pathogenic or Likely Pathogenic Variants in Outcomes of Ovarian Sertoli-Leydig Cell Tumor.
Nelson AT et al.
Jco Precision Oncology, 2025
Sertoli-Leydig tumor and DICER1 gene mutation: A case series and literature review.
Durden AA et al.
The Journal of Obstetrics and Gynaecology Research, 2024
Histone H3 trimethylation on lysine 27 immunostaining pattern in DICER1-associated tumors.
Alturkustani M et al.
Translational Pediatrics, 2024
Characterization of the genomic alterations in poorly differentiated thyroid cancer.
Lee Y et al.
Scientific Reports, 2023
Standing in the canine precision medicine knowledge gap: Improving annotation of canine cancer genomic biomarkers through systematic comparative analysis of human cancer mutations in COSMIC.
Sakthikumar S et al.
Veterinary and Comparative Oncology, 2023
Genomic characterization of DICER1-associated neoplasms uncovers molecular classes.
Kommoss FKF et al.
Nature Communications, 2023
A Rare Adult Primary Intracranial Sarcoma, DICER1-Mutant Identified by Epigenomic Profiling: A Case Report.
Marinelli A et al.
Brain Sciences, 2023
DICER1 Mutations Occur in More Than One-Third of Follicular-Patterned Pediatric Papillary Thyroid Carcinomas and Correlate with a Low-Risk Disease and Female Gender Predilection.
Onder S et al.
Endocrine Pathology, 2022
PRAME protein expression in DICER1-related tumours.
Thorner PS et al.
The Journal of Pathology. Clinical Research, 2022
Primary Intracranial Sarcoma, DICER1-Mutant Presenting as a Pineal Region Tumor Mimicking Pineoblastoma: Case Report and Review of the Literature.
Leelatian N et al.
Journal of Neuropathology and Experimental Neurology, 2022
PRAME protein expression in DICER1-related tumours.
Thorner PS et al.
The Journal of Pathology. Clinical Research, 2022
High Prevalence of Gene Fusions and Copy Number Alterations in Pediatric Radiation Therapy-Induced Papillary and Follicular Thyroid Carcinomas.
Hess JR et al.
Thyroid : Official Journal of the American Thyroid Association, 2022
Phenotypic similarities within the morphologic spectrum of DICER1-associated sarcomas and pleuropulmonary blastoma: Histopathologic features guide diagnosis in the LMIC setting.
Roy P et al.
Pediatric Blood & Cancer, 2022
Highly Sensitive Detection Method of DICER1 Tumor Hotspot Mutations by Drop-off Droplet Digital PCR.
Vibert R et al.
Clinical Chemistry, 2022
MicroSEC filters sequence errors for formalin-fixed and paraffin-embedded samples.
Ikegami M et al.
Communications Biology, 2021
Clinical heterogeneity and reduced penetrance in DICER1 syndrome: a report of three families.
Azzollini J et al.
Tumori, 2021
The Value of DICER1 Mutation Analysis in "Subtle" Diagnostically Challenging Embryonal Rhabdomyosarcomas of the Uterine Cervix.
Yoon JY et al.
International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists, 2021
Clinicopathologic and molecular analysis of embryonal rhabdomyosarcoma of the genitourinary tract: evidence for a distinct DICER1-associated subgroup.
Kommoss FKF et al.
Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 2021
Spectrum of DICER1 Germline Pathogenic Variants in Ovarian Sertoli-Leydig Cell Tumor.
De Paolis E et al.
Journal of Clinical Medicine, 2021
A pan-cancer atlas of somatic mutations in miRNA biogenesis genes.
Galka-Marciniak P et al.
Nucleic Acids Research, 2021
Somatic tumour testing establishes that bilateral DICER1-associated ovarian Sertoli-Leydig cell tumours represent independent primary neoplasms.
McCluggage WG et al.
Histopathology, 2020
Practical roles for molecular diagnostic testing in ovarian adult granulosa cell tumour, Sertoli-Leydig cell tumour, microcystic stromal tumour and their mimics.
Rabban JT et al.
Histopathology, 2020
Ten years of DICER1 mutations: Provenance, distribution, and associated phenotypes.
de Kock L et al.
Human Mutation, 2019
Two cases of primary supratentorial intracranial rhabdomyosarcoma with DICER1 mutation which may belong to a "spindle cell sarcoma with rhabdomyosarcoma-like feature, DICER1 mutant".
Sakaguchi M et al.
Brain Tumor Pathology, 2019
Germline DICER1-mutant intracranial sarcoma with dual chondroid and spindle cell morphology and pulmonary metastases treated with multimodal therapy.
Das A et al.
Pediatric Blood & Cancer, 2019
Finding driver mutations in cancer: Elucidating the role of background mutational processes.
Brown AL et al.
Plos Computational Biology, 2019
Detection of the DICER1 hotspot mutation alongside immunohistochemical analysis may provide a better diagnostic measure for ovarian Sertoli-Leydig cell tumors.
Zhang X et al.
Pathology, Research and Practice, 2018
DICER1 Mutations Are Consistently Present in Moderately and Poorly Differentiated Sertoli-Leydig Cell Tumors.
de Kock L et al.
The American Journal of Surgical Pathology, 2017
DICER1 hotspot mutations in ovarian Sertoli-Leydig cell tumors: a potential association with androgenic effects.
Kato N et al.
Human Pathology, 2017
Somatic mutations of DICER1 and KMT2D are frequent in intraocular medulloepitheliomas.
Sahm F et al.
Genes, Chromosomes & Cancer, 2016
Germline and Somatic DICER1 Mutations in a Well-Differentiated Fetal Adenocarcinoma of the Lung.
de Kock L et al.
Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer, 2016
DICER1 and FOXL2 mutations in ovarian sex cord-stromal tumours: a GINECO Group study.
Goulvent T et al.
Histopathology, 2016
A survey of DICER1 hotspot mutations in ovarian and testicular sex cord-stromal tumors.
Conlon N et al.
Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 2015
Nasal chondromesenchymal hamartomas arise secondary to germline and somatic mutations of DICER1 in the pleuropulmonary blastoma tumor predisposition disorder.
Stewart DR et al.
Human Genetics, 2014
Mutation analysis of DICER1 gene in hematologic tumors.
Lee SH et al.
Leukemia & Lymphoma, 2013
Biallelic DICER1 mutations occur in Wilms tumours.
Wu MK et al.
The Journal of Pathology, 2013
Cancer-associated somatic DICER1 hotspot mutations cause defective miRNA processing and reverse-strand expression bias to predominantly mature 3p strands through loss of 5p strand cleavage.
Anglesio MS et al.
The Journal of Pathology, 2013
Assessment of computational methods for predicting the effects of missense mutations in human cancers.
Gnad F et al.
Bmc Genomics, 2013
A forward genetic screen to study mammalian RNA interference: essential role of RNase IIIa domain of Dicer1 in 3' strand cleavage of dsRNA in vivo.
Ohishi K et al.
The Febs Journal, 2012
Homodimeric structure and double-stranded RNA cleavage activity of the C-terminal RNase III domain of human dicer.
Takeshita D et al.
Journal of Molecular Biology, 2007