Associated Papers
Thyroblastoma as a manifestation of DICER1 syndrome with confirmed germline mutation and comprehensive literature review.
Yin L et al.
Virchows Archiv : an International Journal of Pathology, 2026
Integrating evidence from protein domains to identify cancer driver mutations.
Ostroverkhova D et al.
Protein Science : a Publication of the Protein Society, 2026
YAP1::MAML2 fusion, a newly identified genetic anomaly in a posterior fossa infant tumor, associated with the methylation class "embryonal tumor with multilayered rosettes, non-C19MC-altered" in the Heidelberg central nervous system tumor classifier and "embryonal tumor with multilayered rosettes-DICER" in the NIH classifier.
Godfraind C et al.
Acta Neuropathologica Communications, 2025
Thyroblastoma in Pregnancy: Expanding the Cytomorphological Spectrum of a Novel DICER1 -Associated Entity, a Case Report and Literature Review.
Razack R et al.
Diagnostic Cytopathology, 2025
Genetic mechanisms of resistance to targeted KRAS inhibition.
Diaz BJ et al.
Biorxiv : the Preprint Server for Biology, 2025
DICER1 mutations in Bethesda category II, III, and IV thyroid nodules: A mutually exclusive relationship with BRAFV600E mutation.
Wang Y et al.
Cancer Cytopathology, 2025
RAS pathway targeted therapy in patients with DICER1-associated sarcomas.
Zhang L et al.
Npj Precision Oncology, 2025
A molecular and immunohistochemical study of 37 cases of ovarian Sertoli-Leydig cell tumor.
Němejcová K et al.
Virchows Archiv : an International Journal of Pathology, 2025
Pathological and clinical insights into DICER1 hotspot mutated Sertoli-Leydig cell tumors: a comparative analysis.
Lyu Z et al.
Diagnostic Pathology, 2025
Prognostic Significance of Germline DICER1 Pathogenic or Likely Pathogenic Variants in Outcomes of Ovarian Sertoli-Leydig Cell Tumor.
Nelson AT et al.
Jco Precision Oncology, 2025
DICER1: The Argonaute Endonuclease Family Member and Its Role in Pediatric and Youth Pathology.
Sergi CM et al.
Biology, 2025
Diagnosis and treatment of thyroblastoma: a case report and review of literature.
Chen X et al.
Frontiers in Oncology, 2025
Liver-specific DICER1 syndrome model mice develop cystic liver tumors with defective primary cilia.
Oikawa K et al.
The Journal of Pathology, 2024
Sertoli-Leydig tumor and DICER1 gene mutation: A case series and literature review.
Durden AA et al.
The Journal of Obstetrics and Gynaecology Research, 2024
Recurrent primary intracranial sarcoma, DICER1-mutant in a pediatric patient with DICER1 syndrome: the importance of molecular testing.
Lachance A et al.
Child's Nervous System : Chns : Official Journal of the International Society for Pediatric Neurosurgery, 2024
Primary intracranial DICER1-mutant sarcoma: A case report.
Huang M et al.
Asian Journal of Surgery, 2024
Histone H3 trimethylation on lysine 27 immunostaining pattern in DICER1-associated tumors.
Alturkustani M et al.
Translational Pediatrics, 2024
Teratoma-associated and so-called pure Wilms tumour of the ovary represent two separate tumour types with distinct molecular features.
Kommoss FKF et al.
Histopathology, 2024
Fetal Type Morphologies Suggest the Presence of DICER1 Hotspot Mutations in Non-small Cell Lung Cancer.
Chong AL et al.
The American Journal of Surgical Pathology, 2024
DICER1-mutated rhabdomyosarcoma of the ovary with teratoid features.
Lethongsavarn V et al.
Genes, Chromosomes & Cancer, 2023
Real-world performance analysis of a novel computational method in the precision oncology of pediatric tumors.
Vodicska B et al.
World Journal of Pediatrics : Wjp, 2023
A biobank of pediatric patient-derived-xenograft models in cancer precision medicine trial MAPPYACTS for relapsed and refractory tumors.
Marques Da Costa ME et al.
Communications Biology, 2023
DICER1 platform domain missense variants inhibit miRNA biogenesis and lead to tumor susceptibility.
Pelletier D et al.
Nar Cancer, 2023
Targeting mutant dicer tumorigenesis in pleuropulmonary blastoma via inhibition of RNA polymerase I.
Wong MRE et al.
Translational Research : the Journal of Laboratory and Clinical Medicine, 2023
Salivary gland cancer organoids are valid for preclinical genotype-oriented medical precision trials.
Ishikawa T et al.
Iscience, 2023
Clinical utility of Todai OncoPanel in the setting of approved comprehensive cancer genomic profiling tests in Japan.
Kage H et al.
Cancer Science, 2023
Genomic characterization of DICER1-associated neoplasms uncovers molecular classes.
Kommoss FKF et al.
Nature Communications, 2023
The clinical utility of integrative genomics in childhood cancer extends beyond targetable mutations.
Villani A et al.
Nature Cancer, 2023
Mutational profiling of Chinese patients with thyroid cancer.
Du Y et al.
Frontiers in Endocrinology, 2023
DICER1 Mutations Occur in More Than One-Third of Follicular-Patterned Pediatric Papillary Thyroid Carcinomas and Correlate with a Low-Risk Disease and Female Gender Predilection.
Onder S et al.
Endocrine Pathology, 2022
PRAME protein expression in DICER1-related tumours.
Thorner PS et al.
The Journal of Pathology. Clinical Research, 2022
Implementation of paediatric precision oncology into clinical practice: The Individualized Therapies for Children with cancer program 'iTHER'.
Langenberg KPS et al.
European Journal of Cancer (oxford, England : 1990), 2022
A primary DICER1-sarcoma with KRAS and TP53 mutations in a child with suspected ECCL.
Yang K et al.
Brain Tumor Pathology, 2022
Primary Intracranial Sarcoma, DICER1-Mutant Presenting as a Pineal Region Tumor Mimicking Pineoblastoma: Case Report and Review of the Literature.
Leelatian N et al.
Journal of Neuropathology and Experimental Neurology, 2022
Likely foregut endoderm origin for a postzygotic mutation affecting the RNase IIIb domain of DICER1.
Chong AS et al.
Journal of Medical Genetics, 2022
Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants.
Sánchez-Rivera FJ et al.
Nature Biotechnology, 2022
PRAME protein expression in DICER1-related tumours.
Thorner PS et al.
The Journal of Pathology. Clinical Research, 2022
Expanding the clinical and molecular spectrum of pituitary blastoma.
Liu AP et al.
Acta Neuropathologica, 2022
Highly Sensitive Detection Method of DICER1 Tumor Hotspot Mutations by Drop-off Droplet Digital PCR.
Vibert R et al.
Clinical Chemistry, 2022
A complex DICER1 syndrome phenotype associated with a germline pathogenic variant affecting the RNase IIIa domain of DICER1.
Pontén E et al.
Journal of Medical Genetics, 2022
Clinical heterogeneity and reduced penetrance in DICER1 syndrome: a report of three families.
Azzollini J et al.
Tumori, 2021
Analysis of the mutational status of SIX1/2 and microRNA processing genes in paired primary and relapsed Wilms tumors and association with relapse.
Ciceri S et al.
Cancer Gene Therapy, 2021
Spectrum of DICER1 Germline Pathogenic Variants in Ovarian Sertoli-Leydig Cell Tumor.
De Paolis E et al.
Journal of Clinical Medicine, 2021
Multiomics Characterization of Low-Grade Serous Ovarian Carcinoma Identifies Potential Biomarkers of MEK Inhibitor Sensitivity and Therapeutic Vulnerability.
Shrestha R et al.
Cancer Research, 2021