Varaico: Literature-Extracted Genetic Variants

Gene:DIS3
Variant:p.S477R
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DIS3

NM_014953.5:p.S477R

Associated Papers

DIS3 mutations in multiple myeloma impact the transcriptional signature and clinical outcome.

Todoerti K et al.

Haematologica, 2022

33951891 (PubMed )
Supplement: 2021_278342_TODOERTI_SUPPL.pdf

The RNA Exosome and Human Disease.

Fasken MB et al.

Methods in Molecular Biology (clifton, N.j.), 2020

The 3' to 5' Exoribonuclease DIS3: From Structure and Mechanisms to Biological Functions and Role in Human Disease.

Robinson SR et al.

Biomolecules, 2015

Multiple myeloma-associated hDIS3 mutations cause perturbations in cellular RNA metabolism and suggest hDIS3 PIN domain as a potential drug target.

Tomecki R et al.

Nucleic Acids Research, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."