Associated Papers
Rethinking the Role of DISC1 in CNS Function: Translational Cross-Taxon Insights From Rodent and Zebrafish Models.
Volgin AD et al.
Journal of Integrative Neuroscience, 2025
Common DISC1 Polymorphisms Disrupt Wnt/GSK3β Signaling and Brain Development.
Singh KK et al.
Neuron, 2025
Identification and Mechanistic Characterization of a Peptide Inhibitor of Glycogen Synthase Kinase (GSK3β) Derived from the Disrupted in Schizophrenia 1 (DISC1) Protein.
Saundh SL et al.
Acs Chemical Neuroscience, 2020
The DISC1 R264Q variant increases affinity for the dopamine D2 receptor and increases GSK3 activity.
Su P et al.
Molecular Brain, 2020
Prioritizing natural-selection signals from the deep-sequencing genomic data suggests multi-variant adaptation in Tibetan highlanders.
Deng L et al.
National Science Review, 2019
708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits.
Thomson PA et al.
Molecular Psychiatry, 2014
Meta-analysis indicates that common variants at the DISC1 locus are not associated with schizophrenia.
Mathieson I et al.
Molecular Psychiatry, 2012
Common DISC1 polymorphisms disrupt Wnt/GSK3β signaling and brain development.
Singh KK et al.
Neuron, 2011
Genetic and functional analyses identify DISC1 as a novel callosal agenesis candidate gene.
Osbun N et al.
American Journal of Medical Genetics. Part A, 2011
Sequencing of DISC1 pathway genes reveals increased burden of rare missense variants in schizophrenia patients from a northern Swedish population.
Moens LN et al.
Plos One, 2011
Identification of high risk DISC1 structural variants with a 2% attributable risk for schizophrenia.
Song W et al.
Biochemical and Biophysical Research Communications, 2008
Select a paper to view details