Varaico: Literature-Extracted Genetic Variants

Gene:DLC1
Variant:p.E966K
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DLC1

NM_006094.5:p.E966K

Associated Papers

The tumor suppressor activity of DLC1 requires the interaction of its START domain with Phosphatidylserine, PLCD1, and Caveolin-1.

Sanchez-Solana B et al.

Molecular Cancer, 2021

Identifying Cancer-Relevant Mutations in the DLC START Domain Using Evolutionary and Structure-Function Analyses.

Holub AS et al.

International Journal of Molecular Sciences, 2020

Cancer-Associated Point Mutations in the DLC1 Tumor Suppressor and Other Rho-GAPs Occur Frequently and Are Associated with Decreased Function.

Wang D et al.

Cancer Research, 2020

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."