Associated Papers
A DNA2 mutation in the ATP-binding motif identified in a diagnostically unresolved individual.
Saito K et al.
Frontiers in Molecular Biosciences, 2025
Mechanism of BRCA1-BARD1 function in DNA end resection and DNA protection.
Ceppi I et al.
Nature, 2024
PLK1 regulates CtIP and DNA2 interplay in long-range DNA end resection.
Ceppi I et al.
Genes & Development, 2023
The MRN complex and topoisomerase IIIa-RMI1/2 synchronize DNA resection motor proteins.
Soniat MM et al.
The Journal of Biological Chemistry, 2023
The nuclease activity of DNA2 promotes exonuclease 1-independent mismatch repair.
Kadyrova LY et al.
The Journal of Biological Chemistry, 2022
The iron-sulphur cluster in human DNA2 is required for all biochemical activities of DNA2.
Mariotti L et al.
Communications Biology, 2020
Biallelic variants in DNA2 cause microcephalic primordial dwarfism.
Tarnauskaitė Ž et al.
Human Mutation, 2019
31045292 (PubMed )
Supplement: HUMU-40-1063-s001.docx
Human DNA2 possesses a cryptic DNA unwinding activity that functionally integrates with BLM or WRN helicases.
Pinto C et al.
Elife, 2016
Select a paper to view details