Varaico: Literature-Extracted Genetic Variants

Gene:DNAJB1
Variant:p.R249S
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DNAJB1

NM_006145.3:p.R249S

Associated Papers

Targeting mutant p53 with arsenic trioxide: A preclinical study focusing on triple negative breast cancer.

Rajaram S et al.

Translational Oncology, 2024

Regulation of p53 and Cancer Signaling by Heat Shock Protein 40/J-Domain Protein Family Members.

Kaida A et al.

International Journal of Molecular Sciences, 2021

Hsp70- and Hsp90-Mediated Regulation of the Conformation of p53 DNA Binding Domain and p53 Cancer Variants.

Boysen M et al.

Molecular Cell, 2019

Salvation of the fallen angel: Reactivating mutant p53.

Li Y et al.

British Journal of Pharmacology, 2019

How mutations shape p53 interactions with the genome to promote tumorigenesis and drug resistance.

Stiewe T et al.

Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy, 2018

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."