Varaico: Literature-Extracted Genetic Variants

Gene:DNAJB1
Variant:p.H32Q
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DNAJB1

NM_006145.3:p.H32Q

Associated Papers

Identification of a HTT-specific binding motif in DNAJB1 essential for suppression and disaggregation of HTT.

Ayala Mariscal SM et al.

Nature Communications, 2022

Molecular and pharmacological chaperones for SOD1.

Wright GSA

Biochemical Society Transactions, 2020

Functional diversity between HSP70 paralogs caused by variable interactions with specific co-chaperones.

Serlidaki D et al.

The Journal of Biological Chemistry, 2020

Myopathy associated BAG3 mutations lead to protein aggregation by stalling Hsp70 networks.

Meister-Broekema M et al.

Nature Communications, 2018

A DNAJB chaperone subfamily with HDAC-dependent activities suppresses toxic protein aggregation.

Hageman J et al.

Molecular Cell, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."