Associated Papers
Multiplex neurodegeneration proteotoxicity platform reveals DNAJB6 promotes non-toxic FUS condensate gelation and inhibits neurotoxicity.
Resnick SJ et al.
Nature Communications, 2025
Mrj is a chaperone of the Hsp40 family that regulates Orb2 oligomerization and long-term memory in Drosophila.
Desai M et al.
Plos Biology, 2024
The HSP40 family chaperone isoform DNAJB6b prevents neuronal cells from tau aggregation.
Chang YL et al.
Bmc Biology, 2023
Distinctive chaperonopathy in skeletal muscle associated with the dominant variant in DNAJB4.
Inoue M et al.
Acta Neuropathologica, 2023
Atypical nuclear envelope condensates linked to neurological disorders reveal nucleoporin-directed chaperone activities.
Prophet SM et al.
Nature Cell Biology, 2022
Inhibition of DNAJ-HSP70 interaction improves strength in muscular dystrophy.
Bengoechea R et al.
The Journal of Clinical Investigation, 2020
Neuromuscular Diseases Due to Chaperone Mutations: A Review and Some New Results.
Sarparanta J et al.
International Journal of Molecular Sciences, 2020
Mutations in the J domain of DNAJB6 cause dominant distal myopathy.
Palmio J et al.
Neuromuscular Disorders : Nmd, 2020
Myopathy associated BAG3 mutations lead to protein aggregation by stalling Hsp70 networks.
Meister-Broekema M et al.
Nature Communications, 2018
Prion-like nuclear aggregation of TDP-43 during heat shock is regulated by HSP40/70 chaperones.
Udan-Johns M et al.
Human Molecular Genetics, 2014
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