Associated Papers
Clonal Hematopoiesis of Indeterminate Potential and Clonal Cytopenias of Undetermined Significance: 2026 Update on Clinical Associations and Management Recommendations.
Mangaonkar AA et al.
American Journal of Hematology, 2026
Characterization of the clonal hierarchy and immunophenotype of PTPN11 mutations in acute myeloid leukemia.
Fobare S et al.
Jci Insight, 2026
Structural insight into hierarchical DNMT3A autoinhibition and its dysregulation in disease.
Lu J et al.
Nature Communications, 2026
DNMT3A p.R882C driven proliferation and anti-apoptotic effects in pancreatic cancer cells.
Qu Z et al.
Scientific Reports, 2026
BESTish: A Diffusion-Approximation Framework for Inferring Selection and Mutation in Clonal Hematopoiesis.
Wang RY et al.
Biorxiv : the Preprint Server for Biology, 2026
Single-cell profiling reveals reprogrammed hierarchy and disrupted immune-stromal ecosystem in TP53-mutated AML.
Qiu G et al.
Experimental Hematology & Oncology, 2026
Comprehensive next generation sequencing of middle ear neuroendocrine tumors.
Bishop JA et al.
Annals of Diagnostic Pathology, 2026
Using the Reactome Graph Database to generate pathway fingerprints for cancer-related genes, and using the fingerprints to gain insights into cancer, comorbidity, and cancer gene networks.
Iengar P et al.
Computational Biology and Chemistry, 2026
Integrating evidence from protein domains to identify cancer driver mutations.
Ostroverkhova D et al.
Protein Science : a Publication of the Protein Society, 2026
Dual targeting of SLC25A51 and succinate dehydrogenase selectively depletes mitochondrial NAD+ to eradicate KRAS-driven AML.
Jia A et al.
Cell Metabolism, 2026
Genomic evolution of pancreatic cancer at single-cell resolution.
Zhang H et al.
Nature Genetics, 2026
A framework for the molecular identification of CHIP for clinical research.
Harraka P et al.
Hgg Advances, 2026
Systematic evaluation of neoepitope predictions challenges clinically observed T-cell responses and their impact on immune evasion.
Zaghla BKQ et al.
Journal for Immunotherapy of Cancer, 2026
Inflammageing and clonal haematopoiesis interplay and their impact on human disease.
Hajishengallis G et al.
Nature Reviews. Molecular Cell Biology, 2026
Comparative Analysis of a Dual DNA-RNA Panel and a DNA-Only Panel for Sarcoma: Real-World Data From a Nationwide Genomic Database.
Nakata E et al.
Cancer Science, 2026
Solving Riddles Through Sequencing (SIRIUS): unlocking hematologic diagnoses by whole genome and transcriptome sequencing.
Truger M et al.
Leukemia, 2026
Inherited resilience to clonal hematopoiesis by modifying stem cell RNA regulation.
Agarwal G et al.
Science (new York, N.y.), 2026
Clonal hematopoiesis associates with prevalent and incident cardiometabolic disease in a cardiac catheterization cohort.
Regan JA et al.
Plos One, 2026
Convergent DNA methylation abnormalities at enhancers and bivalent promoters in human growth disorders.
Wheeler MES et al.
Epigenetics & Chromatin, 2025
Common clonal haematopoiesis driver mutations have disparate effects on macrophage cytokines, clonal expansion and atherogenesis.
Carter PR et al.
Jci Insight, 2025
Acute myeloid leukemia with bipotential erythroid and megakaryocytic differentiation: a case series and literature review.
Liu LW et al.
Journal of Hematopathology, 2025
Clonal architecture of FLT3-ITD and acquired 13q uniparental disomy define prognostic heterogeneity and therapeutic vulnerabilities in acute myeloid leukemia.
Lai A et al.
Neoplasia (new York, N.y.), 2025
Ancestry-dependent patterns of somatic mosaicism and clonal hematopoiesis mutations in over 125,000 individuals reveal distinct cancer associations.
Colin-Leitzinger C et al.
Human Genomics, 2025
Novel NUTM1 Fusions in Relapsed Acute Myeloid Leukemia: Expanding the Genetic and Clinical Landscape.
Tizro P et al.
International Journal of Molecular Sciences, 2025
Clonal hematopoiesis driven by Dnmt3a mutations promotes metabolic disease development in mice.
Yan B et al.
The Journal of Clinical Investigation, 2025
Prognostic significance of somatic mutations in myeloid cells of men with chronic heart failure - interaction between loss of Y chromosome and clonal haematopoiesis.
Cremer S et al.
European Journal of Heart Failure, 2025
Evaluation of Long-Read Genome Sequencing for Genomic Profiling of Myeloid Cancers.
Abel HJ et al.
The Journal of Molecular Diagnostics : Jmd, 2025
Clonal hematopoiesis in apparent treatment-resistant hypertension, insights from multiple medical centers and community-based cohorts.
Lv C et al.
Nature Aging, 2025
Posttransplantation clonal dynamics of hematopoietic stem cells carrying prenatal and early-life DNMT3A mutations.
Derks LLM et al.
Hemasphere, 2025
Proteomic subtypes enrich current acute myeloid leukemia nomenclature and reflect intrinsic pathogenesis alongside aging.
Cheng WY et al.
Blood, 2025
Clinical Validation of a Rapid Automated Lymphoma Next-Generation Sequencing Panel.
Krigstein M et al.
Annals of Laboratory Medicine, 2025
The genetic architecture of primary lateral sclerosis in a cohort of Italian patients.
Schito P et al.
Journal of Neurology, 2025
DNMT3A R882H Is Not Required for Disease Maintenance in Primary Human AML, but Is Associated With Increased Leukemia Stem Cell Frequency.
Köhnke T et al.
Cancer Discovery, 2025
Tatton-Brown-Rahman-Syndrome-associated DNMT3A mutations de-repress cortical interneuron differentiation to disrupt neuronal network function.
Chapman G et al.
Biorxiv : the Preprint Server for Biology, 2025
Novel and emerging therapeutic strategies for clonal haematopoiesis.
Hosseini M et al.
Haematologica, 2025
Overexpression of the signaling coordinator GAB2 can play an important role in acute myeloid leukemia progression.
Kramer MH et al.
The Journal of Clinical Investigation, 2025
MUC4-positive Fibroblastoma: A Distinctive Hyalinized Spindle Cell Neoplasm With Aberrant Nuclear Beta-catenin Expression and Frequent Biallelic Inactivation of APC.
Repetto F et al.
The American Journal of Surgical Pathology, 2025