Varaico: Literature-Extracted Genetic Variants

Gene:DOT1L
Variant:p.G137R
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DOT1L

NM_032482.3:p.G137R

Associated Papers

Loss of DOT1L disrupts neuronal transcription and leads to a neurodevelopmental disorder.

Maroni MJ et al.

Brain : a Journal of Neurology, 2026

POLE Mutation Associated With Microsatellite Instability and High Tumor Mutational Burden Confers Exquisite Sensitivity to Immune Checkpoint Inhibitor Therapy in Non-Small Cell Lung Cancer: A Case Report and Genomic Database Analysis.

Lara MS et al.

Clinical Lung Cancer, 2025

Loss of DOT1L disrupts neuronal transcription, behavior, and leads to a neurodevelopmental disorder.

Maroni MJ et al.

Medrxiv : the Preprint Server for Health Sciences, 2025

Predictive value of DOT1L mutations for clinical outcomes in non-small-cell lung cancer patients receiving immune checkpoint inhibitor therapy.

Guo T et al.

Clinical and Translational Medicine, 2023

Clonal and microclonal mutational heterogeneity in high hyperdiploid acute lymphoblastic leukemia.

de Smith AJ et al.

Oncotarget, 2016

27683039 (PubMed )
Supplement: oncotarget-07-72733-s003.xlsx › Sheet1
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."