Varaico: Literature-Extracted Genetic Variants

Gene:DPP4
Variant:p.S630A
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DPP4

NM_001935.4:p.S630A

Associated Papers

Dipeptidyl peptidase-4 greatly contributes to the hydrolysis of vildagliptin in human liver.

Asakura M et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2015

Involvement of DPP-IV catalytic residues in enzyme-saxagliptin complex formation.

Metzler WJ et al.

Protein Science : a Publication of the Protein Society, 2008

Tyrosine 547 constitutes an essential part of the catalytic mechanism of dipeptidyl peptidase IV.

Bjelke JR et al.

The Journal of Biological Chemistry, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."