Associated Papers
DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling.
Harapas CR et al.
Science Immunology, 2022
Structural and biochemical mechanisms of NLRP1 inhibition by DPP9.
Huang M et al.
Nature, 2021
33731929 (PubMed )
Supplement: 41586_2021_3320_MOESM3_ESM.xlsx › Fig._1
The NLRP1 inflammasome: new mechanistic insights and unresolved mysteries.
Mitchell PS et al.
Current Opinion in Immunology, 2019
Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding.
Zhong FL et al.
The Journal of Biological Chemistry, 2018
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