Varaico: Literature-Extracted Genetic Variants

Gene:DPYD
Variant:p.E615D
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DPYD

NM_000110.4:p.E615D

Associated Papers

Pharmacogenetic Study of the Dihydropyridine Dehydrogenase Gene in Jordanian Patients with Colorectal Cancer.

Almashagbah NA et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2022

Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction of DPYD and fluoropyrimidines.

Lunenburg CATC et al.

European Journal of Human Genetics : Ejhg, 2020

31745289 (PubMed )
Supplement: 41431_2019_540_MOESM1_ESM.docx

Comparison of the Guidelines of the Clinical Pharmacogenetics Implementation Consortium and the Dutch Pharmacogenetics Working Group.

Bank PCD et al.

Clinical Pharmacology and Therapeutics, 2018

5-fluorouracil toxicity in the treatment of colon cancer associated with the genetic polymorphism 2846 A>G (rs67376798).

González-Perera I et al.

Journal of Oncology Pharmacy Practice : Official Publication of the International Society of Oncology Pharmacy Practitioners, 2017

Pharmacogenetics: from bench to byte--an update of guidelines.

Swen JJ et al.

Clinical Pharmacology and Therapeutics, 2011

Promoter methylation and large intragenic rearrangements of DPYD are not implicated in severe toxicity to 5-fluorouracil-based chemotherapy in gastrointestinal cancer patients.

Savva-Bordalo J et al.

Bmc Cancer, 2010

Should DPD analysis be required prior to prescribing fluoropyrimidines?

Yen JL et al.

European Journal of Cancer (oxford, England : 1990), 2007

Mutations in exon 14 of dihydropyrimidine dehydrogenase and 5-Fluorouracil toxicity in Portuguese colorectal cancer patients.

Salgueiro N et al.

Genetics in Medicine : Official Journal of the American College of Medical Genetics, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."