Associated Papers
Poor association between dihydropyrimidine dehydrogenase (DPYD) genotype and fluoropyrimidine-induced toxicity in an Asian population.
Kanai M et al.
Cancer Medicine, 2023
36524458 (PubMed )
Supplement: CAM4-12-7808-s002.xlsx › Supplementary_Table_1
Importance of Rare DPYD Genetic Polymorphisms for 5-Fluorouracil Therapy in the Japanese Population.
Hishinuma E et al.
Frontiers in Pharmacology, 2022
In Vitro Assessment of Fluoropyrimidine-Metabolizing Enzymes: Dihydropyrimidine Dehydrogenase, Dihydropyrimidinase, and β-Ureidopropionase.
Hishinuma E et al.
Journal of Clinical Medicine, 2020
Functional Characterization of 21 Allelic Variants of Dihydropyrimidine Dehydrogenase Identified in 1070 Japanese Individuals.
Hishinuma E et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2018
Hypermutation of DPYD Deregulates Pyrimidine Metabolism and Promotes Malignant Progression.
Edwards L et al.
Molecular Cancer Research : Mcr, 2016
Genetic variations and haplotype structures of the DPYD gene encoding dihydropyrimidine dehydrogenase in Japanese and their ethnic differences.
Maekawa K et al.
Journal of Human Genetics, 2007
Screening for dihydropyrimidine dehydrogenase deficiency.
Grem JL
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2005
Dihydropyrimidine dehydrogenase activity in 150 healthy Japanese volunteers and identification of novel mutations.
Ogura K et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2005
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