Varaico: Literature-Extracted Genetic Variants

Gene:DRD2
Variant:p.S311C
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DRD2

NM_000795.4:p.S311C

Associated Papers

Characterisation of pharmacogenomic variation in the Shetland and Orkney Isles in Scotland.

Twesigomwe D et al.

Scientific Reports, 2025

Theorizing The Role of Gama Type Endorphins in Schizophrenia and Alcoholism: Promoting Genetic Testing and Attempts at Inducing "Dopamine Homeostasis".

Blum K et al.

Acta Scientific Neurology, 2025

Investigating DRD2 and HTR2A polymorphisms in treatment-resistant schizophrenia: a comparative analysis with other treatment-resistant mental disorders and the healthy state.

Del Casale A et al.

European Archives of Psychiatry and Clinical Neuroscience, 2025

Association of Dopamine pathway gene polymorphisms in patients with alcohol dependence.

Singh R et al.

Asian Journal of Psychiatry, 2024

Association of DRD2, DRD4 and COMT genes variants and their gene-gene interactions with antipsychotic treatment response in patients with schizophrenia.

Taheri N et al.

Bmc Psychiatry, 2023

The Progress and Pitfalls of Pharmacogenetics-Based Precision Medicine in Schizophrenia Spectrum Disorders: A Systematic Review and Meta-Analysis.

Teng Y et al.

Journal of Personalized Medicine, 2023

36983653 (PubMed )
Supplement: jpm-13-00471-s001.zip › Supplementary_Table_S2.xlsx › Table_S2

Antipsychotic drug-aripiprazole against schizophrenia, its therapeutic and metabolic effects associated with gene polymorphisms.

Stelmach A et al.

Pharmacological Reports : Pr, 2023

The pharmacogenomic landscape of an Indigenous Australian population.

Samarasinghe SR et al.

Frontiers in Pharmacology, 2023

37284308 (PubMed )
Supplement: Table3.xlsx › HGMD-ClinVar_14_known_variants

Rare genetic variability in human drug target genes modulates drug response and can guide precision medicine.

Zhou Y et al.

Science Advances, 2021

34516913 (PubMed )
Supplement: sciadv.abi6856_tables_s1_to_s8.zip › sciadv.abi6856_Table_S6.xlsx › Sheet1

Polymorphisms of Dopamine Receptor Genes and Parkinson's Disease: Clinical Relevance and Future Perspectives.

Magistrelli L et al.

International Journal of Molecular Sciences, 2021

A Gain-of-Function Variant in Dopamine D2 Receptor and Progressive Chorea and Dystonia Phenotype.

van der Weijden MCM et al.

Movement Disorders : Official Journal of the Movement Disorder Society, 2021

33200438 (PubMed )
Supplement: MDS-36-729-s002.docx

Functional Polymorphisms in Oxytocin and Dopamine Pathway Genes and the Development of Dispositional Compassion Over Time: The Young Finns Study.

Dobewall H et al.

Frontiers in Psychology, 2021

33897514 (PubMed )
Supplement: Data_Sheet_1.docx

Genome-wide association study of antipsychotic-induced sinus bradycardia in Chinese schizophrenia patients.

Weng S et al.

Plos One, 2021

Genetic Polymorphisms Associated With the Pharmacokinetics, Pharmacodynamics and Adverse Effects of Olanzapine, Aripiprazole and Risperidone.

Soria-Chacartegui P et al.

Frontiers in Pharmacology, 2021

Investigating the association between common DRD2/ANKK1 genetic polymorphisms and schizophrenia: a meta-analysis.

Habibzadeh P et al.

Journal of Genetics, 2021

Influence of DRD2 Polymorphisms on the Clinical Outcomes of Opioiddependent Patients on Methadone Maintenance Therapy.

Zahari Z et al.

Journal of Pharmacy & Bioallied Sciences, 2020

Association of DRD2 gene polymorphisms with schizophrenia in the young Bangladeshi population: A pilot study.

Hussain MS et al.

Heliyon, 2020

Synonymous polymorphism rs201256011 in dopamine receptor type 2 gene is associated with schizophrenia and PANSS score in Pakistani population: A first report.

Amir QU et al.

International Journal of Clinical Practice, 2020

Evolutionary conservation and functional impact of dopamine D2 receptor.

Yuan J et al.

Neuroscience Letters, 2020

Genetic variants in dopamine receptors influence on heterodimerization in the context of antipsychotic drug action.

Faron-Górecka A et al.

Progress in Molecular Biology and Translational Science, 2020

An epistasis between dopaminergic and oxytocinergic systems confers risk of post-traumatic stress disorder in a traumatized Chinese cohort.

Zhang K et al.

Scientific Reports, 2019

Residues and residue pairs of evolutionary importance differentially direct signaling bias of D2 dopamine receptors.

Terrón-Díaz ME et al.

The Journal of Biological Chemistry, 2019

Effects of a GWAS-Supported Schizophrenia Variant in the DRD2 Locus on Disease Risk, Anhedonia, and Prefrontal Cortical Thickness.

Alfimova MV et al.

Journal of Molecular Neuroscience : Mn, 2019

No association between polymorphisms in the promoter region of dopamine receptor D2 gene and schizophrenia in the northern Chinese Han population: A case-control study.

Zhang XC et al.

Brain and Behavior, 2019

Dopaminergic Pathway Genes Influence Adverse Events Related to Dopaminergic Treatment in Parkinson's Disease.

Redenšek S et al.

Frontiers in Pharmacology, 2019

Population genetic difference of pharmacogenomic VIP gene variants in the Lisu population from Yunnan Province.

Zhang C et al.

Medicine, 2018

Antipsychotic Drug Responsiveness and Dopamine Receptor Signaling; Old Players and New Prospects.

Rampino A et al.

Frontiers in Psychiatry, 2018

Identification of genetic correlates of response to Risperidone: Findings of a multicentric schizophrenia study from India.

Kaur G et al.

Asian Journal of Psychiatry, 2017

Genetic variants of dopamine D2 receptor impact heterodimerization with dopamine D1 receptor.

Błasiak E et al.

Pharmacological Reports : Pr, 2017

Bicodon bias can determine the role of synonymous SNPs in human diseases.

McCarthy C et al.

Bmc Genomics, 2017

28288557 (PubMed )
Supplement: 12864_2017_3609_MOESM2_ESM.pdf

The Dopamine Receptor D2 C957T Polymorphism Modulates Early Components of Event-Related Potentials in Visual Word Recognition Task.

Golimbet VE et al.

Neuropsychobiology, 2017

The role of C957T, TaqI and Ser311Cys polymorphisms of the DRD2 gene in schizophrenia: systematic review and meta-analysis.

González-Castro TB et al.

Behavioral and Brain Functions : Bbf, 2016

Pharmacogenetic tests for antipsychotic medications: clinical implications and considerations.

Eum S et al.

Dialogues in Clinical Neuroscience, 2016

A splicing-regulatory polymorphism in DRD2 disrupts ZRANB2 binding, impairs cognitive functioning and increases risk for schizophrenia in six Han Chinese samples.

Cohen OS et al.

Molecular Psychiatry, 2016

Investigating the structural impact of S311C mutation in DRD2 receptor by molecular dynamics & docking studies.

Podder A et al.

Biochimie, 2016

Genetic variation and dopamine D2 receptor availability: a systematic review and meta-analysis of human in vivo molecular imaging studies.

Gluskin BS et al.

Translational Psychiatry, 2016

Associations between dopamine D2 receptor gene polymorphisms and schizophrenia risk: a PRISMA compliant meta-analysis.

He H et al.

Neuropsychiatric Disease and Treatment, 2016

Genetic Polymorphisms in the Dopamine Receptor 2 Predict Acute Pain Severity After Motor Vehicle Collision.

Qadri YJ et al.

The Clinical Journal of Pain, 2015

Correlation analysis between single nucleotide polymorphism of DRD1 gene and stereotyped behavior of blue fox.

Liu ZY et al.

Genetics and Molecular Research : Gmr, 2015

Influence of -141C Ins/Del Polymorphism in DRD2 Gene on Clinical Symptoms and Plasma Homovanillic Acid Levels in the Treatment of Schizophrenia With Aripiprazole.

Miura I et al.

Journal of Clinical Psychopharmacology, 2015

DRD2 genotypic and haplotype variation is associated with improvements in negative symptoms after 6 weeks' amisulpride treatment.

Kang SG et al.

Journal of Clinical Psychopharmacology, 2015

Response to "DRD2 Ser311Cys polymorphism and risk of schizophrenia".

Yao J et al.

American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 2015

DRD2 Ser311Cys polymorphism and risk of schizophrenia.

Watanabe Y et al.

American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 2015

Updated findings of the association and functional studies of DRD2/ANKK1 variants with addictions.

Ma Y et al.

Molecular Neurobiology, 2015

Specific and common genes implicated across major mental disorders: a review of meta-analysis studies.

Gatt JM et al.

Journal of Psychiatric Research, 2015

Association between DRD2 (rs1799732 and rs1801028) and ANKK1 (rs1800497) polymorphisms and schizophrenia: a meta-analysis.

Yao J et al.

American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 2015

Selection in the dopamine receptor 2 gene: a candidate SNP study.

Göllner T et al.

Peerj, 2015

The relationship between DRD2 gene polymorphisms (C957T and C939T) and schizophrenia: a meta-analysis.

Liu L et al.

Neuroscience Letters, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."