Associated Papers
Directed evolution of metalloproteinase inhibitor TIMP-1 for selective inhibition of MMP-9 exploits catalytic and fibronectin domain interactions.
Shoari A et al.
The Journal of Biological Chemistry, 2025
Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2.
Enrico TP et al.
Elife, 2021
Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage.
Amen AM et al.
Proceedings of the National Academy of Sciences of the United States of America, 2021
33758097 (PubMed )
Supplement: pnas.2008772118.sapp.pdf
Histone demethylase KDM4C controls tumorigenesis of glioblastoma by epigenetically regulating p53 and c-Myc.
Lee DH et al.
Cell Death & Disease, 2021
33462212 (PubMed )
Supplement: 41419_2020_3380_MOESM2_ESM.pdf
Cyclin D-Cdk4,6 Drives Cell-Cycle Progression via the Retinoblastoma Protein's C-Terminal Helix.
Topacio BR et al.
Molecular Cell, 2019
First Demonstration of Positive Allosteric-like Modulation at the Human Wild Type Translocator Protein (TSPO).
Narlawar R et al.
Journal of Medicinal Chemistry, 2015
Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain.
Furnari FB et al.
Proceedings of the National Academy of Sciences of the United States of America, 1997
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