Varaico: Literature-Extracted Genetic Variants

Gene:DYRK1B
Variant:p.D239A
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DYRK1B

NM_004714.3:p.D239A

Associated Papers

Discriminating activating, deactivating and resistance variants in protein kinases.

Singh G et al.

Genome Medicine, 2025

41152984 (PubMed )
Supplement: 13073_2025_1564_MOESM2_ESM.xlsx › Table_S5

Screen identifies DYRK1B network as mediator of transcription repression on damaged chromatin.

Dong C et al.

Proceedings of the National Academy of Sciences of the United States of America, 2020

Identification of DYRK1B as a substrate of ERK1/2 and characterisation of the kinase activity of DYRK1B mutants from cancer and metabolic syndrome.

Ashford AL et al.

Cellular and Molecular Life Sciences : Cmls, 2016

A novel DYRK1B inhibitor AZ191 demonstrates that DYRK1B acts independently of GSK3β to phosphorylate cyclin D1 at Thr(286), not Thr(288).

Ashford AL et al.

The Biochemical Journal, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."