Varaico: Literature-Extracted Genetic Variants

Gene:DYRK2
Variant:p.K251R
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DYRK2

NM_006482.3:p.K251R

Associated Papers

Discriminating activating, deactivating and resistance variants in protein kinases.

Singh G et al.

Genome Medicine, 2025

41152984 (PubMed )
Supplement: 13073_2025_1564_MOESM2_ESM.xlsx › Table_S5

CAKUT variants in PRPF8, DYRK2, and CEP78: implications for splicing and ciliogenesis.

Merz LM et al.

Biorxiv : the Preprint Server for Biology, 2025

Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase.

Yoshida S et al.

Proceedings of the National Academy of Sciences of the United States of America, 2024

DYRK2 promotes chemosensitivity via p53-mediated apoptosis after DNA damage in colorectal cancer.

Takano Y et al.

Cancer Science, 2023

DYRK2 maintains genome stability via neddylation of cullins in response to DNA damage.

Kawamura A et al.

Journal of Cell Science, 2022

The novel ciliogenesis regulator DYRK2 governs Hedgehog signaling during mouse embryogenesis.

Yoshida S et al.

Elife, 2020

Multi-layered proteomic analyses decode compositional and functional effects of cancer mutations on kinase complexes.

Mehnert M et al.

Nature Communications, 2020

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."