Varaico: Literature-Extracted Genetic Variants

Gene:E2F1
Variant:p.Y411C
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E2F1

NM_005225.3:p.Y411C

Associated Papers

A transcriptionally active pRb-E2F1-P/CAF signaling pathway is central to TGFβ-mediated apoptosis.

Korah J et al.

Cell Death & Disease, 2012

Transforming growth factor-beta inhibits telomerase through SMAD3 and E2F transcription factors.

Lacerte A et al.

Cellular Signalling, 2008

Macrophage migration inhibitory factor MIF interferes with the Rb-E2F pathway.

Petrenko O et al.

Molecular Cell, 2005

Human papillomavirus type 16 E7 binds to E2F1 and activates E2F1-driven transcription in a retinoblastoma protein-independent manner.

Hwang SG et al.

The Journal of Biological Chemistry, 2002

New Myc-interacting proteins: a second Myc network emerges.

Sakamuro D et al.

Oncogene, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."