Varaico: Literature-Extracted Genetic Variants

Gene:E2F1
Variant:p.R166H
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E2F1

NM_005225.3:p.R166H

Associated Papers

Molecular analysis of the evolutionary history of endometrial and ovarian carcinoma in Lynch syndrome.

Kauppinen AK et al.

International Journal of Cancer, 2025

40772756 (PubMed )
Supplement: IJC-157-2294-s002.xlsx › B_Tissue_as_normal

A base editing platform for the correction of cancer driver mutations unmasks conserved p53 transcription programs.

Wang P et al.

Genome Biology, 2025

40696461 (PubMed )
Supplement: 13059_2025_3667_MOESM1_ESM.xlsx › Overlap_between_lines

LncRNA SLNCR phenocopies the E2F1 DNA binding site to promote melanoma progression.

Shah K et al.

Cell Reports, 2025

Arginine methylation expands the regulatory mechanisms and extends the genomic landscape under E2F control.

Roworth AP et al.

Science Advances, 2019

Integrated clinical, whole-genome, and transcriptome analysis of multisampled lethal metastatic prostate cancer.

Bova GS et al.

Cold Spring Harbor Molecular Case Studies, 2016

27148588 (PubMed )
Supplement: supp_mcs.a000752_SuppTable2.xls › Sheet_1

Heterozygous loss of NF2 is an early molecular alteration in well-differentiated papillary mesothelioma of the peritoneum.

Nemoto H et al.

Cancer Genetics, 2012

First somatic mutation of E2F1 in a critical DNA binding residue discovered in well-differentiated papillary mesothelioma of the peritoneum.

Yu W et al.

Genome Biology, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."