Associated Papers
Recombination between fragile regions associated with chromosomal rearrangements in glioblastoma can be mediated by RAGs.
Paranjape A et al.
Iscience, 2025
Multiplex single-cell chemical genomics reveals the kinase dependence of the response to targeted therapy.
McFaline-Figueroa JL et al.
Cell Genomics, 2024
Targeting the non-coding genome and temozolomide signature enables CRISPR-mediated glioma oncolysis.
Tan IL et al.
Cell Reports, 2023
Nuclear transport surveillance of p53 by nuclear pores in glioblastoma.
Ikliptikawati DK et al.
Cell Reports, 2023
DNA damage repair kinase DNA-PK and cGAS synergize to induce cancer-related inflammation in glioblastoma.
Taffoni C et al.
The Embo Journal, 2023
Spastin Promotes the Migration and Invasion Capability of T98G Glioblastoma Cells by Interacting with Pin1 through Its Microtubule-Binding Domain.
Temizci B et al.
Cells, 2023
PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells.
Huang T et al.
Molecular Cell, 2021
Cdk4 and Cdk6 Couple the Cell-Cycle Machinery to Cell Growth via mTORC1.
Romero-Pozuelo J et al.
Cell Reports, 2020
Role of Asparagine Endopeptidase in Mediating Wild-Type p53 Inactivation of Glioblastoma.
Lin Y et al.
Journal of the National Cancer Institute, 2020
CIC protein instability contributes to tumorigenesis in glioblastoma.
Bunda S et al.
Nature Communications, 2019
MGMT Expression Contributes to Temozolomide Resistance in H3K27M-Mutant Diffuse Midline Gliomas.
Abe H et al.
Frontiers in Oncology, 2019
Epidermal growth factor receptor and ligand family expression and activity in glioblastoma.
von Achenbach C et al.
Journal of Neurochemistry, 2018
DEPTOR at the Nexus of Cancer, Metabolism, and Immunity.
Caron A et al.
Physiological Reviews, 2018
Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma.
Braun CJ et al.
Cancer Cell, 2017
mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT.
Gu Y et al.
Molecular Cell, 2017
Evaluation of novel imidazotetrazine analogues designed to overcome temozolomide resistance and glioblastoma regrowth.
Ramirez YP et al.
Molecular Cancer Therapeutics, 2015
Detection of primary cilia in human glioblastoma.
Sarkisian MR et al.
Journal of Neuro-oncology, 2014
The dual PI3K/mTOR inhibitor NVP-BEZ235 is a potent inhibitor of ATM- and DNA-PKCs-mediated DNA damage responses.
Mukherjee B et al.
Neoplasia (new York, N.y.), 2012
The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas.
Leng S et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2011
[Identification of the hemolytic transfusion reaction caused by lewis antibody using serological and molecular biological methods].
Hong XZ et al.
Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2008
Cyclin-dependent kinase 3-mediated activating transcription factor 1 phosphorylation enhances cell transformation.
Zheng D et al.
Cancer Research, 2008
Down-regulation of Wilms' tumor 1 expression in glioblastoma cells increases radiosensitivity independently of p53.
Clark AJ et al.
Journal of Neuro-oncology, 2007
PIK3CA alterations in primary (de novo) and secondary glioblastomas.
Kita D et al.
Acta Neuropathologica, 2007
Shc3 affects human high-grade astrocytomas survival.
Magrassi L et al.
Oncogene, 2005
p53 disruption profoundly alters the response of human glioblastoma cells to DNA topoisomerase I inhibition.
Wang Y et al.
Oncogene, 2004
Identification and recombinant production of human laminin alpha4 subunit splice variants.
Hayashi Y et al.
Biochemical and Biophysical Research Communications, 2002
Growth inhibition of glioblastoma cells by human Pur(alpha).
Darbinian N et al.
Journal of Cellular Physiology, 2001
Heparin-binding epidermal growth factor-like growth factor stimulates mitogenic signaling and is highly expressed in human malignant gliomas.
Mishima K et al.
Acta Neuropathologica, 1998
MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines.
Teng DH et al.
Cancer Research, 1997
Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain.
Furnari FB et al.
Proceedings of the National Academy of Sciences of the United States of America, 1997
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers.
Steck PA et al.
Nature Genetics, 1997
Altered structure and expression of the p53 gene in human neuroepithelial tumors.
Tabuchi K et al.
Neurologia Medico-chirurgica, 1992
Regulation of epidermal growth factor receptor gene expression.
Hudson LG et al.
Molecular Endocrinology (baltimore, Md.), 1989