Varaico: Literature-Extracted Genetic Variants

Gene:EGF
Variant:p.S288T
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EGF

NM_001963.6:p.S288T

Associated Papers

HER2 mutation as an emerging target in advanced breast cancer.

Bon G et al.

Cancer Science, 2024

The predictive role of ERBB2 point mutations in metastatic colorectal cancer: A systematic review.

Vaghi C et al.

Cancer Treatment Reviews, 2023

Systematic molecular profiling of inhibitor response to the clinical missense mutations of ErbB family kinases in human gastric cancer.

Ding X et al.

Journal of Molecular Graphics & Modelling, 2020

Clinical and pathological characterization of HER2 mutations in human breast cancer: a systematic review of the literature.

Petrelli F et al.

Breast Cancer Research and Treatment, 2017

HER2 somatic mutations are associated with poor survival in HER2-negative breast cancers.

Wang T et al.

Cancer Science, 2017

Comprehensive genomic profiling of 295 cases of clinically advanced urothelial carcinoma of the urinary bladder reveals a high frequency of clinically relevant genomic alterations.

Ross JS et al.

Cancer, 2016

Oncogenic alterations in ERBB2/HER2 represent potential therapeutic targets across tumors from diverse anatomic sites of origin.

Chmielecki J et al.

The Oncologist, 2015

Differential sensitivity of ERBB2 kinase domain mutations towards lapatinib.

Kancha RK et al.

Plos One, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."