Varaico: Literature-Extracted Genetic Variants

Gene:EGF
Variant:p.D563A
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EGF

NM_001963.6:p.D563A

Associated Papers

Allosteric regulation of epidermal growth factor (EGF) receptor ligand binding by tyrosine kinase inhibitors.

Macdonald-Obermann JL et al.

The Journal of Biological Chemistry, 2018

Complex relationship between ligand binding and dimerization in the epidermal growth factor receptor.

Bessman NJ et al.

Cell Reports, 2014

The tethering arm of the EGF receptor is required for negative cooperativity and signal transduction.

Adak S et al.

The Journal of Biological Chemistry, 2011

ErbB2 resembles an autoinhibited invertebrate epidermal growth factor receptor.

Alvarado D et al.

Nature, 2009

19718021 (PubMed )
Supplement: NIHMS133050-supplement-2.pdf
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."