Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.G5R
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EGFR

NM_005228.5:p.G5R

Associated Papers

Genomic Profile of Non-Small Cell Lung Cancer in a Spanish Cohort: A 2-Year Descriptive Study Using Next-Generation Sequencing.

Carnero-Gregorio M et al.

Genes, 2026

KRAS and MET Co-Mutation in One Lesion and EGFR Mutation in Another Lesion of Early-Stage Synchronous Multiple Lung Adenocarcinomas: A Case Report.

Ito T et al.

The Tohoku Journal of Experimental Medicine, 2025

Tumor mutational burden modulates the prognostic effect of RAS mutations in metastatic colon cancer: mechanistic insights and genotype-phenotype correlations.

Ianniello M et al.

Journal of Translational Medicine, 2025

The pathogenic mutations in smokers with non-small cell lung cancer: a next-generation sequencing study.

Yan S et al.

Translational Lung Cancer Research, 2025

Integrative proteomic characterization of human lung adenocarcinoma with KRAS G12 mutations reveals molecular pathogenesis.

Shi X et al.

Journal of Advanced Research, 2025

Impacts of co-mutations in oligometastatic and oligoprogressive non-small cell lung cancer with EGFR/ALK mutations-a narrative review of the current literature.

Lim JU et al.

Translational Lung Cancer Research, 2025

Distribution of EGFR and KRAS Mutations in Patients with Surgically Resected Non-Small Cell Lung Cancer from Southern Italy: Real-Life Data from a Single Institution and Literature Review.

Piazzolla M et al.

Cancers, 2025

40075579 (PubMed )
Supplement: cancers-17-00730-s001.zip › cancers-3468545-supplementary.xlsx › KRASmutated_profile_SupplTab3

Next-Generation Sequencing (NGS) in non-small cell lung carcinoma: A real-world experience in the public health system of Galicia (Northwest Spain).

Abdulkader-Nallib I et al.

Plos One, 2025

Clinicopathological and molecular features of lung cancers associated with cystic airspaces: an analysis of 34 cases.

Zhou F et al.

Journal of Thoracic Disease, 2024

Molecular characterization of Chinese patients with small bowel adenocarcinoma.

Jin B et al.

Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2024

Exploring the Relationship Between KRAS, NRAS, and BRAF Mutations and Clinical Characteristics in Iranian Colorectal Cancer Patients.

Mosaferi Z et al.

Journal of Gastrointestinal Cancer, 2024

Beyond tobacco: genomic disparities in lung cancer between smokers and never-smokers.

Garrido J et al.

Bmc Cancer, 2024

39097719 (PubMed )
Supplement: 12885_2024_12737_MOESM2_ESM.xlsx › Table_S5

Real-world applications of the new grading system in lung adenocarcinoma: A study of 907 patients focusing on revealing the relationship between pathologic grade and genetic status.

Liu XL et al.

Annals of Diagnostic Pathology, 2024

KRAS Mutation Subtypes and Their Association with Other Driver Mutations in Oncogenic Pathways.

Mondal K et al.

Cells, 2024

Strength of selection in lung tumors correlates with clinical features better than tumor mutation burden.

Gorlov IP et al.

Scientific Reports, 2024

Comparison between next-generation sequencing and multiplex polymerase chain reaction assays for nonsmall-cell lung cancer molecular diagnosis.

Murakami S et al.

Cancer Medicine, 2024

38572952 (PubMed )
Supplement: CAM4-13-e7162-s001.xlsx › DNA_mutations

PROMER technology: A new real-time PCR tool enabling multiplex detection of point mutation with high specificity and sensitivity.

Nam H et al.

Biology Methods & Protocols, 2024

Association of mutation profiles with metastasis in patients with non-small cell lung cancer.

Li Y et al.

Frontiers in Oncology, 2024

39464712 (PubMed )
Supplement: Table3.xlsx › LMG____

Baseline mutational profiles of patients with carcinoma of unknown primary origin enrolled in the CUPISCO study.

Westphalen CB et al.

Esmo Open, 2023

37922692 (PubMed )
Supplement: mmc1.docx

Prevalence of oncogenic driver mutations in Hispanics/Latin patients with lung cancer. A systematic review and meta-analysis.

Parra-Medina R et al.

Lung Cancer (amsterdam, Netherlands), 2023

The spectrum of MAPK-ERK pathway genomic alterations in gynecologic malignancies: Opportunities for novel therapeutic approaches.

Nasioudis D et al.

Gynecologic Oncology, 2023

Detection and Monitoring of Tumor-Derived Mutations in Circulating Tumor DNA Using the UltraSEEK Lung Panel on the MassARRAY System in Metastatic Non-Small Cell Lung Cancer Patients.

Leest PV et al.

International Journal of Molecular Sciences, 2023

37686200 (PubMed )
Supplement: ijms-24-13390-s001.zip › ijms-2558089-supplementary.pdf

Molecular Biology and Therapeutic Perspectives for K-Ras Mutant Non-Small Cell Lung Cancers.

Cekani E et al.

Cancers, 2022

KRAS alterations in colorectal liver metastases: shifting to exon, codon, and point mutations.

Olthof PB et al.

The British Journal of Surgery, 2022

35595182 (PubMed )
Supplement: znac147_supplementary_data.docx

Potential genetic biomarker of Saudi Arabian patients with colorectal cancer.

Younis NS et al.

European Review for Medical and Pharmacological Sciences, 2022

Prevalence of targeted therapy-related genetic variations in NSCLC and their relationship with clinicopathological characteristics.

Li F et al.

Plos One, 2022

35061839 (PubMed )
Supplement: pone.0262822.s002.xlsx › Supplementary_information

Antitumor efficacy of XPO1 inhibitor Selinexor in KRAS-mutant lung adenocarcinoma patient-derived xenografts.

Rosen JC et al.

Translational Oncology, 2021

Phase 1, pharmacogenomic, dose-expansion study of pegargiminase plus pemetrexed and cisplatin in patients with ASS1-deficient non-squamous non-small cell lung cancer.

Szlosarek PW et al.

Cancer Medicine, 2021

Outcomes and prognostic contributors in patients with KRAS mutated non-small cell pulmonary adenocarcinomas: a single institution experience.

Burns EA et al.

Journal of Thoracic Disease, 2021

Characterization of the Immune Landscape of EGFR-Mutant NSCLC Identifies CD73/Adenosine Pathway as a Potential Therapeutic Target.

Le X et al.

Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer, 2021

Mutational landscape of multiple primary lung cancers and its correlation with non-intrinsic risk factors.

Izumi M et al.

Scientific Reports, 2021

Morphological and genetic heterogeneity of synchronous multifocal lung adenocarcinoma in a Chinese cohort.

Zhu D et al.

Bmc Cancer, 2021

Clinical Application of Targeted Deep Sequencing in Metastatic Colorectal Cancer Patients: Actionable Genomic Alteration in K-MASTER Project.

Lee Y et al.

Cancer Research and Treatment, 2021

Next-Generation Sequencing Reveals High Uncommon EGFR Mutations and Tumour Mutation Burden in a Subgroup of Lung Cancer Patients.

Guo G et al.

Frontiers in Oncology, 2021

Characterization With KRAS Mutant Is a Critical Determinant in Immunotherapy and Other Multiple Therapies for Non-Small Cell Lung Cancer.

Shen M et al.

Frontiers in Oncology, 2021

Spectrum of driver mutations and clinical impact of circulating tumor DNA analysis in non-small cell lung cancer: Analysis of over 8000 cases.

Mack PC et al.

Cancer, 2020

32365229 (PubMed )
Supplement: CNCR-126-3219-s002.docx

Overall survival in patients with lung adenocarcinoma harboring "niche" mutations: an observational study.

Aramini B et al.

Oncotarget, 2020

IMPACT OF KRAS MUTATIONS IN CLINICAL FEATURES IN COLORECTAL CANCER.

Zanatto RM et al.

Arquivos Brasileiros De Cirurgia Digestiva : Abcd = Brazilian Archives of Digestive Surgery, 2020

KRAS Codon 12 Mutation is Associated with More Aggressive Invasiveness in Synchronous Metastatic Colorectal Cancer (mCRC): Retrospective Research.

He K et al.

Oncotargets and Therapy, 2020

An integrative pharmacogenomics analysis identifies therapeutic targets in KRAS-mutant lung cancer.

Wang H et al.

Ebiomedicine, 2019

31668570 (PubMed )
Supplement: mmc5.xlsx › Sheet1

Analysis of the frequency of oncogenic driver mutations and correlation with clinicopathological characteristics in patients with lung adenocarcinoma from Northeastern Switzerland.

Grosse A et al.

Diagnostic Pathology, 2019

MassARRAY-based simultaneous detection of hotspot somatic mutations and recurrent fusion genes in papillary thyroid carcinoma: the PTC-MA assay.

Pesenti C et al.

Endocrine, 2018

Mutation analysis of the EGFR pathway genes, EGFR, RAS, PIK3CA, BRAF, and AKT1, in salivary gland adenoid cystic carcinoma.

Saida K et al.

Oncotarget, 2018

29682203 (PubMed )
Supplement: oncotarget-09-17043-s001.pdf

ALK immunohistochemistry is highly sensitive and specific for the detection of ALK translocated lung adenocarcinomas: lessons from an audit of lung cancer molecular testing.

Kheng YC et al.

The Journal of the Royal College of Physicians of Edinburgh, 2018

Multiple Hotspot Mutations Scanning by Single Droplet Digital PCR.

Decraene C et al.

Clinical Chemistry, 2018

Comprehensive Validation of Snapback Primer-Based Melting Curve Analysis to Detect Nucleotide Variation in the Codon 12 and 13 of KRAS Gene.

Zhang Q et al.

Biomed Research International, 2018

Mutational profiling of acral melanomas in Korean populations.

Shim JH et al.

Experimental Dermatology, 2017

BRAF and NRAS Locus-Specific Variants Have Different Outcomes on Survival to Colorectal Cancer.

Summers MG et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2017

Ordering of mutations in acute myeloid leukemia with partial tandem duplication of MLL (MLL-PTD).

Sun QY et al.

Leukemia, 2017

27389053 (PubMed )
Supplement: leu2016160x1.doc
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."