Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.M277K
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EGFR

NM_005228.5:p.M277K

Associated Papers

Casein kinase 1 and 2 phosphorylate Argonaute proteins to regulate miRNA-mediated gene silencing.

Shah VN et al.

Embo Reports, 2023

Genomic analysis of plasma circulating tumor DNA in patients with heavily pretreated HER2 + metastatic breast cancer.

Lee K et al.

Scientific Reports, 2023

37336919 (PubMed )
Supplement: 41598_2023_35925_MOESM1_ESM.xlsx › Table_S4__patho_variants_

The non-small cell lung cancer EGFR extracellular domain mutation, M277E, is oncogenic and drug-sensitive.

Yu S et al.

Oncotargets and Therapy, 2017

Cell signaling by receptor tyrosine kinases.

Lemmon MA et al.

Cell, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."