Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.E282K
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EGFR

NM_005228.5:p.E282K

Associated Papers

Common gene mutations in 103 authenticated colorectal cancer cell lines.

Kranjec C et al.

Oncogenesis, 2026

41593049 (PubMed )
Supplement: 41389_2026_599_MOESM2_ESM.xlsx › Supplementary_Table_10

Comprehensive Genomic Profiling in Advanced Non-Small Cell Lung Cancer: A Real-World Cohort Study in Finland.

Hormalainen K et al.

Cancer Medicine, 2025

Towards Personalized Precision Oncology: A Feasibility Study of NGS-Based Variant Analysis of FFPE CRC Samples in a Chilean Public Health System Laboratory.

Durán-Jara E et al.

Current Issues in Molecular Biology, 2025

40864753 (PubMed )
Supplement: cimb-47-00599-s001.zip › Supplementary_Table_S4_-_VAF_and_actionability.pdf

A comprehensive molecular characterization of a claudin-low luminal B breast tumor.

Giovannini S et al.

Biology Direct, 2024

ERBB family fusions are recurrent and actionable oncogenic targets across cancer types.

Schubert L et al.

Frontiers in Oncology, 2023

37168365 (PubMed )
Supplement: Table_4.xlsx › EGFR_mutations

Clinical and Molecular Features of KRAS-Mutated Lung Cancer Patients Treated with Immune Checkpoint Inhibitors.

Zhao D et al.

Cancers, 2022

Whole-exome Sequencing of Nigerian Prostate Tumors from the Prostate Cancer Transatlantic Consortium (CaPTC) Reveals DNA Repair Genes Associated with African Ancestry.

White JA et al.

Cancer Research Communications, 2022

36922933 (PubMed )
Supplement: crc-22-0136-s01.xlsx › ST9_Somatic_Variants

Enrichment of cancer-predisposing germline variants in adult and pediatric patients with acute lymphoblastic leukemia.

Douglas SPM et al.

Scientific Reports, 2022

35739278 (PubMed )
Supplement: 41598_2022_14364_MOESM1_ESM.xlsx › Supplementary_table_1

Pan-cancer assessment of mutational landscape in intrinsically disordered hotspots reveals potential driver genes.

Zou H et al.

Nucleic Acids Research, 2022

35061901 (PubMed )
Supplement: gkac028_supplemental_files.zip › Table_S3_new.xlsx › Sheet1

Clinical Application of Comprehensive Genomic Profiling Tests for Diffuse Gliomas.

Omura T et al.

Cancers, 2022

35626060 (PubMed )
Supplement: cancers-14-02454-s001.zip › cancers-1674301-SI.xlsx › VUS

Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

Chevrier S et al.

International Journal of Molecular Medicine, 2022

35244186 (PubMed )
Supplement: Supplementary_Data2.xlsx › Feuil1

Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

G V et al.

Frontiers in Genetics, 2022

Discordance of PIK3CA and TP53 mutations between breast cancer brain metastases and matched primary tumors.

Thulin A et al.

Scientific Reports, 2021

34876602 (PubMed )
Supplement: 41598_2021_2903_MOESM1_ESM.xlsx › Blad1

Genomic profile of advanced breast cancer in circulating tumour DNA.

Kingston B et al.

Nature Communications, 2021

33893289 (PubMed )
Supplement: 41467_2021_22605_MOESM4_ESM.xlsx › SNVs_Indels

Comparison of next-generation sequencing and immunohistochemistry analysis for targeted therapy-related genomic status in lung cancer patients.

Nong L et al.

Journal of Thoracic Disease, 2019

Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare EGFR mutations.

Ikemura S et al.

Proceedings of the National Academy of Sciences of the United States of America, 2019

31043566 (PubMed )
Supplement: pnas.1819430116.sapp.pdf

Targeted mutation detection in breast cancer using MammaSeq™.

Smith NG et al.

Breast Cancer Research : Bcr, 2019

30736836 (PubMed )
Supplement: 13058_2019_1102_MOESM2_ESM.xlsx › Sheet1

Germline mutations in candidate predisposition genes in individuals with cutaneous melanoma and at least two independent additional primary cancers.

Pritchard AL et al.

Plos One, 2018

29641532 (PubMed )
Supplement: pone.0194098.s003.xlsx › UK10K_Kinase_

Clinical mutational profiling of 1006 lung cancers by next generation sequencing.

Illei PB et al.

Oncotarget, 2017

Cancer gene profiling in non-small cell lung cancers reveals activating mutations in JAK2 and JAK3 with therapeutic implications.

Li SD et al.

Genome Medicine, 2017

29082853 (PubMed )
Supplement: 13073_2017_478_MOESM1_ESM.xlsx › Table_S2

Novel near-diploid ovarian cancer cell line derived from a highly aneuploid metastatic ovarian tumor.

Rozenblum E et al.

Plos One, 2017

28787462 (PubMed )
Supplement: pone.0182610.s001.xlsx › H1-Ea-La_mut

Genomic portfolio of Merkel cell carcinoma as determined by comprehensive genomic profiling: implications for targeted therapeutics.

Cohen PR et al.

Oncotarget, 2016

ErbB polymorphisms: insights and implications for response to targeted cancer therapeutics.

Alaoui-Jamali MA et al.

Frontiers in Genetics, 2015

25699077 (PubMed )
Supplement: Table1.PDF

Discrepancies in cancer genomic sequencing highlight opportunities for driver mutation discovery.

Hudson AM et al.

Cancer Research, 2014

Drug resistance missense mutations in cancer are subject to evolutionary constraints.

Friedman R

Plos One, 2013

24376513 (PubMed )
Supplement: pone.0082059.s003.pdf

Comprehensive molecular portraits of human breast tumours.

Unknown Author

Nature, 2012

23000897 (PubMed )
Supplement: NIHMS393293-supplement-4.xls › Sheet_1

Genomic landscape and actionable mutations of brain metastases derived from non-small cell lung cancer: A systematic review.

Andrews LJ et al.

Neuro-oncology Advances, 0

38130901 (PubMed )
Supplement: vdad145_suppl_supplementary_data.xlsx › Individual_data

Profiling the molecular and clinical landscape of glioblastoma utilizing the Oncology Research Information Exchange Network brain cancer database.

Demetriou AN et al.

Neuro-oncology Advances, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."