Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.Q486*
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EGFR

NM_005228.5:p.Q486*

Associated Papers

ERBB family fusions are recurrent and actionable oncogenic targets across cancer types.

Schubert L et al.

Frontiers in Oncology, 2023

37168365 (PubMed )
Supplement: Table_4.xlsx › EGFR_mutations

Detection of oncogenic and clinically actionable mutations in cancer genomes critically depends on variant calling tools.

Garcia-Prieto CA et al.

Bioinformatics (oxford, England), 2022

35512388 (PubMed )
Supplement: btac306_supplementary_data.zip › Supplementary_files.zip › Supplementary_files › Supplementary_file_7.xlsx › Sheet1

Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Yin XQ et al.

Frontiers in Oncology, 2022

35936718 (PubMed )
Supplement: Table_4.xlsx › MAF_infomation

An EGFR signature predicts cell line and patient sensitivity to multiple tyrosine kinase inhibitors.

Cheng C et al.

International Journal of Cancer, 2020

Spectrum of EGFR aberrations and potential clinical implications: insights from integrative pan-cancer analysis.

Liu H et al.

Cancer Communications (london, England), 2020

32067422 (PubMed )
Supplement: CAC2-40-43-s001.xlsx › Table_S1

JUN-Mediated Downregulation of EGFR Signaling Is Associated with Resistance to Gefitinib in EGFR-mutant NSCLC Cell Lines.

Kani K et al.

Molecular Cancer Therapeutics, 2017

Identification of G2607A mutation in EGFR gene with a significative rate in Moroccan patients with Bladder Cancer.

El Hamdani W et al.

Cellular and Molecular Biology (noisy-le-grand, France), 2017

Compound EGFR mutation is frequently detected with co-mutations of actionable genes and associated with poor clinical outcome in lung adenocarcinoma.

Kim EY et al.

Cancer Biology & Therapy, 2016

Comprehensive molecular profiling of lung adenocarcinoma.

Unknown Author

Nature, 2014

25079552 (PubMed )
Supplement: NIHMS629713-supplement-Supllementary_information_2.xlsx › S_Table_7-Clinical_Molec_Summar

Advanced urothelial carcinoma: next-generation sequencing reveals diverse genomic alterations and targets of therapy.

Ross JS et al.

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 2014

Identification of G2607A mutation in EGFR gene with a significative rate in Moroccan patients with nasopharyngeal carcinoma.

Naji F et al.

Cellular and Molecular Biology (noisy-le-grand, France), 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."