Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.K500Splc
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EGFR

NM_005228.5:p.K500Splc

Associated Papers

Establishment and Characterization of a Brain Parenchymal Metastatic Cell Line AlmoR1 Derived From an NSCLC Patient With EGFR-TKI Resistance.

Wu J et al.

Cancer Medicine, 2025

Investigation of Exome-Wide Tumor Heterogeneity on Colorectal Tissue-Based Single Cells.

Szakállas N et al.

International Journal of Molecular Sciences, 2025

SB202190 Predicts BRAF-Activating Mutations in Primary Colorectal Cancer Organoids via Erk1-2 Modulation.

Costa D et al.

Cells, 2023

36831331 (PubMed )
Supplement: cells-12-00664-s001.zip › Table_S2__Cells_.xlsx › Suppl_Table2

Machine learning random forest for predicting oncosomatic variant NGS analysis.

Pellegrino E et al.

Scientific Reports, 2021

34750410 (PubMed )
Supplement: 41598_2021_1253_MOESM1_ESM.pdf

Microsecond-timescale MD simulation of EGFR minor mutation predicts the structural flexibility of EGFR kinase core that reflects EGFR inhibitor sensitivity.

Yoshizawa T et al.

Npj Precision Oncology, 2021

33863983 (PubMed )
Supplement: 41698_2021_170_MOESM4_ESM.xlsx › Pre_Post_Afatinibshared_variant

A deep analysis using panel-based next-generation sequencing in an Ecuadorian pediatric patient with anaplastic astrocytoma: a case report.

García-Cárdenas JM et al.

Journal of Medical Case Reports, 2020

32867815 (PubMed )
Supplement: 13256_2020_2451_MOESM1_ESM.xlsx › SPC34

Transient Disappearance of RAS Mutant Clones in Plasma: A Counterintuitive Clinical Use of EGFR Inhibitors in RAS Mutant Metastatic Colorectal Cancer.

Raimondi C et al.

Cancers, 2019

Sequencing of DICER1 in sarcomas identifies biallelic somatic DICER1 mutations in an adult-onset embryonal rhabdomyosarcoma.

de Kock L et al.

British Journal of Cancer, 2017

28524158 (PubMed )
Supplement: bjc2017147x1.pdf

Performance comparison of two commercial human whole-exome capture systems on formalin-fixed paraffin-embedded lung adenocarcinoma samples.

Bonfiglio S et al.

Bmc Cancer, 2016

Next-Generation Sequencing Workflow for NSCLC Critical Samples Using a Targeted Sequencing Approach by Ion Torrent PGM™ Platform.

Vanni I et al.

International Journal of Molecular Sciences, 2015

26633390 (PubMed )
Supplement: ijms-16-26129-s001.xls › Table_S2
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."