Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.E545D
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EGFR

NM_005228.5:p.E545D

Associated Papers

Comparison between next-generation sequencing and multiplex polymerase chain reaction assays for nonsmall-cell lung cancer molecular diagnosis.

Murakami S et al.

Cancer Medicine, 2024

38572952 (PubMed )
Supplement: CAM4-13-e7162-s003.xlsx › DNA_mutations

Neurodevelopmental disorders and cancer networks share pathways, but differ in mechanisms, signaling strength, and outcome.

Yavuz BR et al.

Npj Genomic Medicine, 2023

Analysis of PIK3CA Mutation Concordance and Frequency in Primary and Different Distant Metastatic Sites in Breast Cancer.

Park J et al.

Cancer Research and Treatment, 2023

PIK3CA mutations associated with a poor postoperative prognosis in patients with pulmonary pleomorphic carcinoma: a retrospective cohort study.

Kojima K et al.

Bmc Cancer, 2022

36243681 (PubMed )
Supplement: 12885_2022_10176_MOESM1_ESM.xlsx › Sheet1

EGFR Pathway-Based Gene Signatures of Druggable Gene Mutations in Melanoma, Breast, Lung, and Thyroid Cancers.

Raevskiy M et al.

Biochemistry. Biokhimiia, 2021

The Spectrum, Tendency and Predictive Value of PIK3CA Mutation in Chinese Colorectal Cancer Patients.

Fu X et al.

Frontiers in Oncology, 2021

Biomarkers in Breast Cancer: An Integrated Analysis of Comprehensive Genomic Profiling and PD-L1 Immunohistochemistry Biomarkers in 312 Patients with Breast Cancer.

Huang RSP et al.

The Oncologist, 2020

Major challenges in accurate mutation detection of multifocal lung adenocarcinoma by next-generation sequencing.

Qiu T et al.

Cancer Biology & Therapy, 2020

Comparison of plasma to tissue DNA mutations in surgical patients with non-small cell lung cancer.

Chen K et al.

The Journal of Thoracic and Cardiovascular Surgery, 2017

Hot spot mutations in Finnish non-small cell lung cancers.

Mäki-Nevala S et al.

Lung Cancer (amsterdam, Netherlands), 2016

Functional characterization of somatic mutations in cancer using network-based inference of protein activity.

Alvarez MJ et al.

Nature Genetics, 2016

27322546 (PubMed )
Supplement: NIHMS789775-supplement-1.pdf

Rapid targeted somatic mutation analysis of solid tumors in routine clinical diagnostics.

Magliacane G et al.

Oncotarget, 2015

Gene mutation characteristics of nonsmall-cell lung carcinoma patients with wild-type epidermal growth factor receptor and sensitivity to Tarceva therapy.

Cui Y et al.

Journal of Cancer Research and Therapeutics, 2015

Epidermal growth factor receptor pathway mutation and expression profiles in cervical squamous cell carcinoma: therapeutic implications.

Bumrungthai S et al.

Journal of Translational Medicine, 2015

Mutation frequency in 15 common cancer genes in high-risk head and neck squamous cell carcinoma.

McBride SM et al.

Head & Neck, 2014

The AKT inhibitor AZD5363 is selectively active in PI3KCA mutant gastric cancer, and sensitizes a patient-derived gastric cancer xenograft model with PTEN loss to Taxotere.

Li J et al.

Journal of Translational Medicine, 2013

Effectors of epidermal growth factor receptor pathway: the genetic profiling ofKRAS, BRAF, PIK3CA, NRAS mutations in colorectal cancer characteristics and personalized medicine.

Shen Y et al.

Plos One, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."